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Mitochondria hyperfusion and elevated autophagic activity are key mechanisms for cellular bioenergetic preservation in centenarians.
Sgarbi G, Matarrese P, Pinti M, Lanzarini C, Ascione B, Gibellini L, Dika E, Patrizi A, Tommasino C, Capri M, Cossarizza A, Baracca A, Lenaz G, Solaini G, Franceschi C, Malorni W, Salvioli S. Sgarbi G, et al. Among authors: franceschi c. Aging (Albany NY). 2014 Apr;6(4):296-310. doi: 10.18632/aging.100654. Aging (Albany NY). 2014. PMID: 24799450 Free PMC article.
Structural Brain Abnormalities in Successfully Treated HIV Infection: Associations With Disease and Cerebrospinal Fluid Biomarkers.
van Zoest RA, Underwood J, De Francesco D, Sabin CA, Cole JH, Wit FW, Caan MWA, Kootstra NA, Fuchs D, Zetterberg H, Majoie CBLM, Portegies P, Winston A, Sharp DJ, Gisslén M, Reiss P; Comorbidity in Relation to AIDS (COBRA) Collaboration. van Zoest RA, et al. J Infect Dis. 2017 Dec 27;217(1):69-81. doi: 10.1093/infdis/jix553. J Infect Dis. 2017. PMID: 29069436 Free article.
The 'COmorBidity in Relation to AIDS' (COBRA) cohort: Design, methods and participant characteristics.
De Francesco D, Wit FW, Cole JH, Kootstra NA, Winston A, Sabin CA, Underwood J, van Zoest RA, Schouten J, Kooij KW, Prins M, Guaraldi G, Caan MWA, Burger D, Franceschi C, Libert C, Bürkle A, Reiss P; COmorBidity in Relation to AIDS (COBRA) collaboration. De Francesco D, et al. Among authors: franceschi c. PLoS One. 2018 Mar 29;13(3):e0191791. doi: 10.1371/journal.pone.0191791. eCollection 2018. PLoS One. 2018. PMID: 29596425 Free PMC article.
Increased brain-predicted aging in treated HIV disease.
Cole JH, Underwood J, Caan MW, De Francesco D, van Zoest RA, Leech R, Wit FW, Portegies P, Geurtsen GJ, Schmand BA, Schim van der Loeff MF, Franceschi C, Sabin CA, Majoie CB, Winston A, Reiss P, Sharp DJ; COBRA collaboration. Cole JH, et al. Among authors: franceschi c. Neurology. 2017 Apr 4;88(14):1349-1357. doi: 10.1212/WNL.0000000000003790. Epub 2017 Mar 3. Neurology. 2017. PMID: 28258081 Free PMC article.
Do people living with HIV experience greater age advancement than their HIV-negative counterparts?
De Francesco D, Wit FW, Bürkle A, Oehlke S, Kootstra NA, Winston A, Franceschi C, Garagnani P, Pirazzini C, Libert C, Grune T, Weber D, Jansen EHJM, Sabin CA, Reiss P; the Co-morBidity in Relation to AIDS (COBRA) Collaboration. De Francesco D, et al. Among authors: franceschi c. AIDS. 2019 Feb 1;33(2):259-268. doi: 10.1097/QAD.0000000000002063. AIDS. 2019. PMID: 30325781 Free PMC article.
High Cellular Monocyte Activation in People Living With Human Immunodeficiency Virus on Combination Antiretroviral Therapy and Lifestyle-Matched Controls Is Associated With Greater Inflammation in Cerebrospinal Fluid.
Booiman T, Wit FW, Maurer I, De Francesco D, Sabin CA, Harskamp AM, Prins M, Garagnani P, Pirazzini C, Franceschi C, Fuchs D, Gisslén M, Winston A, Reiss P, Kootstra NA; Comorbidity in Relation to AIDS (COBRA) Collaboration. Booiman T, et al. Among authors: franceschi c. Open Forum Infect Dis. 2017 May 25;4(3):ofx108. doi: 10.1093/ofid/ofx108. eCollection 2017 Summer. Open Forum Infect Dis. 2017. PMID: 28680905 Free PMC article.
1,038 results