Wardan H - Search Results

1

An in vivo model for analysis of developmental erythropoiesis and globin gene regulation.

McColl B, Kao BR, Lourthai P, Chan K, Wardan H, Roosjen M, Delagneau O, Gearing LJ, Blewitt ME, Svasti S, Fucharoen S, Vadolas J. McColl B, et al. Among authors: wardan h. FASEB J. 2014 May;28(5):2306-17. doi: 10.1096/fj.13-246637. Epub 2014 Jan 17. FASEB J. 2014. PMID: 24443374

2

Generation of a genomic reporter assay system for analysis of γ- and β-globin gene regulation.

Chan KS, Xu J, Wardan H, McColl B, Orkin S, Vadolas J. Chan KS, et al. Among authors: wardan h. FASEB J. 2012 Apr;26(4):1736-44. doi: 10.1096/fj.11-199356. Epub 2012 Jan 20. FASEB J. 2012. PMID: 22267339 Free PMC article.

3

Development of sensitive fluorescent assays for embryonic and fetal hemoglobin inducers using the human beta -globin locus in erythropoietic cells.

Vadolas J, Wardan H, Orford M, Voullaire L, Zaibak F, Williamson R, Ioannou PA. Vadolas J, et al. Among authors: wardan h. Blood. 2002 Dec 1;100(12):4209-16. doi: 10.1182/blood-2001-12-0365. Epub 2002 Aug 1. Blood. 2002. PMID: 12393613 Free article.

4

Cellular genomic reporter assays for screening and evaluation of inducers of fetal hemoglobin.

Vadolas J, Wardan H, Orford M, Williamson R, Ioannou PA. Vadolas J, et al. Among authors: wardan h. Hum Mol Genet. 2004 Jan 15;13(2):223-33. doi: 10.1093/hmg/ddh023. Epub 2003 Nov 25. Hum Mol Genet. 2004. PMID: 14645208

5

A 191-kb genomic fragment containing the human alpha-globin locus can rescue alpha-thalassemic mice.

Al-Hasani K, Vadolas J, Knaupp AS, Wardan H, Voullaire L, Williamson R, Ioannou PA. Al-Hasani K, et al. Among authors: wardan h. Mamm Genome. 2005 Nov;16(11):847-53. doi: 10.1007/s00335-005-0089-9. Epub 2005 Nov 11. Mamm Genome. 2005. PMID: 16284800

6

siRNA-mediated reduction of alpha-globin results in phenotypic improvements in beta-thalassemic cells.

Voon HP, Wardan H, Vadolas J. Voon HP, et al. Among authors: wardan h. Haematologica. 2008 Aug;93(8):1238-42. doi: 10.3324/haematol.12555. Epub 2008 Jun 12. Haematologica. 2008. PMID: 18556409 Free article.

7

Humanized beta-thalassemia mouse model containing the common IVSI-110 splicing mutation.

Vadolas J, Nefedov M, Wardan H, Mansooriderakshan S, Voullaire L, Jamsai D, Williamson R, Ioannou PA. Vadolas J, et al. Among authors: wardan h. J Biol Chem. 2006 Mar 17;281(11):7399-405. doi: 10.1074/jbc.M512931200. Epub 2006 Jan 18. J Biol Chem. 2006. PMID: 16421096 Free article.

8

Site-specific, Rep-mediated integration of the intact beta-globin locus in the human erythroleukaemic cell line K562.

Howden SE, Voullaire L, Wardan H, Williamson R, Vadolas J. Howden SE, et al. Among authors: wardan h. Gene Ther. 2008 Oct;15(20):1372-83. doi: 10.1038/gt.2008.84. Epub 2008 May 22. Gene Ther. 2008. PMID: 18496574

9

Transgene copy number-dependent rescue of murine beta-globin knockout mice carrying a 183 kb human beta-globin BAC genomic fragment.

Vadolas J, Wardan H, Bosmans M, Zaibak F, Jamsai D, Voullaire L, Williamson R, Ioannou PA. Vadolas J, et al. Among authors: wardan h. Biochim Biophys Acta. 2005 May 1;1728(3):150-62. doi: 10.1016/j.bbaexp.2005.02.008. Epub 2005 Mar 17. Biochim Biophys Acta. 2005. PMID: 15820143

10

Co-inheritance of alpha- and beta-thalassaemia in mice ameliorates thalassaemic phenotype.

Voon HP, Wardan H, Vadolas J. Voon HP, et al. Among authors: wardan h. Blood Cells Mol Dis. 2007 Sep-Oct;39(2):184-8. doi: 10.1016/j.bcmd.2007.01.006. Epub 2007 May 9. Blood Cells Mol Dis. 2007. PMID: 17493845

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