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Page 1
Durable complete response after combined treatment with tumor-infiltrating lymphocytes and oncolytic adenovirus (TILT-123) in a patient with metastatic mucosal melanoma.
Monberg TJ, Kudling T, Albieri B, Pakola S, Ellebaek E, Donia M, Eefsen RL, von Buchwald C, Kistler C, Santos JM, Clubb J, Haybout L, Westergaard MCW, Quixabeira DCA, Jirovec E, Havunen R, Sorsa S, Cervera-Carrascon V, Hemminki A, Svane IM. Monberg TJ, et al. Among authors: sorsa s. Immunooncol Technol. 2024 Aug 12;24:100726. doi: 10.1016/j.iotech.2024.100726. eCollection 2024 Dec. Immunooncol Technol. 2024. PMID: 39801682 Free PMC article.
Single intravenous administration of oncolytic adenovirus TILT-123 results in systemic tumor transduction and immune response in patients with advanced solid tumors.
Jirovec E, Quixabeira DCA, Clubb JHA, Pakola SA, Kudling T, Arias V, Haybout L, Jalkanen K, Alanko T, Monberg T, Khammari A, Dreno B, Svane IM, Block MS, Adamo DA, Mäenpää J, Kistler C, Sorsa S, Hemminki O, Kanerva A, Santos JM, Cervera-Carrascon V, Hemminki A. Jirovec E, et al. Among authors: sorsa s. J Exp Clin Cancer Res. 2024 Nov 6;43(1):297. doi: 10.1186/s13046-024-03219-0. J Exp Clin Cancer Res. 2024. PMID: 39506856 Free PMC article. Clinical Trial.
Safety, Efficacy, and Biological Data of T-Cell-Enabling Oncolytic Adenovirus TILT-123 in Advanced Solid Cancers from the TUNIMO Monotherapy Phase I Trial.
Pakola SA, Peltola KJ, Clubb JHA, Jirovec E, Haybout L, Kudling TV, Alanko T, Korpisaari R, Juteau S, Jaakkola M, Sormunen J, Kemppainen J, Hemmes A, Pellinen T, van der Heijden M, Quixabeira DCA, Kistler C, Sorsa S, Havunen R, Santos JM, Cervera-Carrascon V, Hemminki A. Pakola SA, et al. Among authors: sorsa s. Clin Cancer Res. 2024 Sep 3;30(17):3715-3725. doi: 10.1158/1078-0432.CCR-23-3874. Clin Cancer Res. 2024. PMID: 38546220 Free PMC article. Clinical Trial.
Effective intravenous delivery of adenovirus armed with TNFα and IL-2 improves anti-PD-1 checkpoint blockade in non-small cell lung cancer.
Kudling TV, Clubb JHA, Pakola S, Quixabeira DCA, Lähdeniemi IAK, Heiniö C, Arias V, Havunen R, Cervera-Carrascon V, Santos JM, Sutinen E, Räsänen J, Borenius K, Mäyränpää MI, Aaltonen E, Sorsa S, Hemminki O, Kanerva A, Verschuren EW, Ilonen I, Hemminki A. Kudling TV, et al. Among authors: sorsa s. Oncoimmunology. 2023 Aug 2;12(1):2241710. doi: 10.1080/2162402X.2023.2241710. eCollection 2023. Oncoimmunology. 2023. PMID: 37546696 Free PMC article.
Development of a Syrian hamster anti-PD-L1 monoclonal antibody enables oncolytic adenoviral immunotherapy modelling in an immunocompetent virus replication permissive setting.
Clubb JHA, Kudling TV, Girych M, Haybout L, Pakola S, Hamdan F, Cervera-Carrascon V, Hemmes A, Grönberg-Vähä-Koskela S, Santos JM, Quixabeira DCA, Basnet S, Heiniö C, Arias V, Jirovec E, Kaptan S, Havunen R, Sorsa S, Erikat A, Schwartz J, Anttila M, Aro K, Viitala T, Vattulainen I, Cerullo V, Kanerva A, Hemminki A. Clubb JHA, et al. Among authors: sorsa s. Front Immunol. 2023 Feb 3;14:1060540. doi: 10.3389/fimmu.2023.1060540. eCollection 2023. Front Immunol. 2023. PMID: 36817448 Free PMC article.
Oncolytic adenovirus coding for bispecific T cell engager against human MUC-1 potentiates T cell response against solid tumors.
Basnet S, Santos JM, Quixabeira DCA, Clubb JHA, Grönberg-Vähä-Koskela SAM, Arias V, Pakola S, Kudling TV, Heiniö C, Havunen R, Cervera-Carrascon V, Sorsa S, Anttila M, Kanerva A, Hemminki A. Basnet S, et al. Among authors: sorsa s. Mol Ther Oncolytics. 2022 Dec 28;28:59-73. doi: 10.1016/j.omto.2022.12.007. eCollection 2023 Mar 16. Mol Ther Oncolytics. 2022. PMID: 36699617 Free PMC article.
Adenovirus Encoding Tumor Necrosis Factor Alpha and Interleukin 2 Induces a Tertiary Lymphoid Structure Signature in Immune Checkpoint Inhibitor Refractory Head and Neck Cancer.
Clubb JHA, Kudling TV, Heiniö C, Basnet S, Pakola S, Cervera Carrascón V, Santos JM, Quixabeira DCA, Havunen R, Sorsa S, Zheng V, Salo T, Bäck L, Aro K, Tulokas S, Loimu V, Hemminki A. Clubb JHA, et al. Among authors: sorsa s. Front Immunol. 2022 Mar 7;13:794251. doi: 10.3389/fimmu.2022.794251. eCollection 2022. Front Immunol. 2022. PMID: 35355980 Free PMC article.
32 results