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LPS impairs phospholipid synthesis by triggering beta-transducin repeat-containing protein (beta-TrCP)-mediated polyubiquitination and degradation of the surfactant enzyme acyl-CoA:lysophosphatidylcholine acyltransferase I (LPCAT1).
Zou C, Butler PL, Coon TA, Smith RM, Hammen G, Zhao Y, Chen BB, Mallampalli RK. Zou C, et al. J Biol Chem. 2011 Jan 28;286(4):2719-27. doi: 10.1074/jbc.M110.192377. Epub 2010 Nov 10. J Biol Chem. 2011. PMID: 21068446 Free PMC article.
3,176 results