Predictors of poor outcome and benefits from antibiotics in children with acute otitis media: pragmatic randomised trial.
Little P, Gould C, Moore M, Warner G, Dunleavey J, Williamson I.
Little P, et al.
BMJ. 2002 Jul 6;325(7354):22; discussion 22. doi: 10.1136/bmj.325.7354.22.
BMJ. 2002.
PMID: 12098725
Free PMC article.
Clinical Trial.
Among the children with high temperature or vomiting, distress by day three was less likely with immediate antibiotics (32% for immediate v 53% for delayed, chi2=4.0; P=0.045, number needed to treat 5) as was night disturbance (26% v 59%, chi2=9.3; P=0.002; number n …
Among the children with high temperature or vomiting, distress by day three was less likely with immediate antibiotics (32% for immediate v …