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Lysosomal-mediated waste clearance in retinal pigment epithelial cells is regulated by CRYBA1/βA3/A1-crystallin via V-ATPase-MTORC1 signaling.
Valapala M, Wilson C, Hose S, Bhutto IA, Grebe R, Dong A, Greenbaum S, Gu L, Sengupta S, Cano M, Hackett S, Xu G, Lutty GA, Dong L, Sergeev Y, Handa JT, Campochiaro P, Wawrousek E, Zigler JS Jr, Sinha D. Valapala M, et al. Among authors: xu g. Autophagy. 2014 Mar;10(3):480-96. doi: 10.4161/auto.27292. Epub 2014 Jan 23. Autophagy. 2014. PMID: 24468901 Free PMC article.
A modified histoimmunochemistry-assisted method for in situ RPE evaluation.
Zhang J, Xu G, Zhang L, Gu L, Xu H, Lu L, Wang J, Gao F, Xu JY, Wang F, Li W, Xu GT. Zhang J, et al. Among authors: xu gt, xu jy, xu g, xu h. Front Biosci (Elite Ed). 2012 Jan 1;4(4):1571-81. doi: 10.2741/481. Front Biosci (Elite Ed). 2012. PMID: 22201976 Free article.
The amino acid transporter SLC36A4 regulates the amino acid pool in retinal pigmented epithelial cells and mediates the mechanistic target of rapamycin, complex 1 signaling.
Shang P, Valapala M, Grebe R, Hose S, Ghosh S, Bhutto IA, Handa JT, Lutty GA, Lu L, Wan J, Qian J, Sergeev Y, Puertollano R, Zigler JS Jr, Xu GT, Sinha D. Shang P, et al. Aging Cell. 2017 Apr;16(2):349-359. doi: 10.1111/acel.12561. Epub 2017 Jan 13. Aging Cell. 2017. PMID: 28083894 Free PMC article.
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