Sipple J - Search Results

1

Concomitant inactivation of foxo3a and fancc or fancd2 reveals a two-tier protection from oxidative stress-induced hydrocephalus.

Li X, Li L, Li J, Sipple J, Schick J, Mehta PA, Davies SM, Dasgupta B, Waclaw RR, Pang Q. Li X, et al. Among authors: sipple j. Antioxid Redox Signal. 2014 Oct 20;21(12):1675-92. doi: 10.1089/ars.2013.5597. Epub 2014 Mar 12. Antioxid Redox Signal. 2014. PMID: 24483844 Free PMC article.

2

Deletion of Fanca or Fancd2 dysregulates Treg in mice.

Du W, Erden O, Wilson A, Sipple JM, Schick J, Mehta P, Myers KC, Steinbrecher KA, Davies SM, Pang Q. Du W, et al. Among authors: sipple jm. Blood. 2014 Mar 20;123(12):1938-47. doi: 10.1182/blood-2013-09-528018. Epub 2014 Feb 5. Blood. 2014. PMID: 24501220 Free PMC article.

3

The FA pathway counteracts oxidative stress through selective protection of antioxidant defense gene promoters.

Du W, Rani R, Sipple J, Schick J, Myers KC, Mehta P, Andreassen PR, Davies SM, Pang Q. Du W, et al. Among authors: sipple j. Blood. 2012 May 3;119(18):4142-51. doi: 10.1182/blood-2011-09-381970. Epub 2012 Mar 9. Blood. 2012. PMID: 22408259 Free PMC article.

4

Fanconi anemia links reactive oxygen species to insulin resistance and obesity.

Li J, Sipple J, Maynard S, Mehta PA, Rose SR, Davies SM, Pang Q. Li J, et al. Among authors: sipple j. Antioxid Redox Signal. 2012 Oct 15;17(8):1083-98. doi: 10.1089/ars.2011.4417. Epub 2012 Jun 25. Antioxid Redox Signal. 2012. PMID: 22482891 Free PMC article.

5

Fancd2 is required for nuclear retention of Foxo3a in hematopoietic stem cell maintenance.

Li X, Li J, Wilson A, Sipple J, Schick J, Pang Q. Li X, et al. Among authors: sipple j. J Biol Chem. 2015 Jan 30;290(5):2715-27. doi: 10.1074/jbc.M114.619536. Epub 2014 Dec 12. J Biol Chem. 2015. PMID: 25505262 Free PMC article.

6

mTOR kinase inhibitor sensitizes T-cell lymphoblastic leukemia for chemotherapy-induced DNA damage via suppressing FANCD2 expression.

Guo F, Li J, Zhang S, Du W, Amarachintha S, Sipple J, Phelan J, Grimes HL, Zheng Y, Pang Q. Guo F, et al. Among authors: sipple j. Leukemia. 2014 Jan;28(1):203-6. doi: 10.1038/leu.2013.215. Epub 2013 Jul 15. Leukemia. 2014. PMID: 23852546 Free PMC article. No abstract available.

7

Cytoplasmic FANCA-FANCC complex interacts and stabilizes the cytoplasm-dislocalized leukemic nucleophosmin protein (NPMc).

Du W, Li J, Sipple J, Chen J, Pang Q. Du W, et al. Among authors: sipple j. J Biol Chem. 2010 Nov 26;285(48):37436-44. doi: 10.1074/jbc.M110.113209. Epub 2010 Sep 23. J Biol Chem. 2010. PMID: 20864535 Free PMC article.

8

Salidroside stimulates DNA repair enzyme Parp-1 activity in mouse HSC maintenance.

Li X, Sipple J, Pang Q, Du W. Li X, et al. Among authors: sipple j. Blood. 2012 May 3;119(18):4162-73. doi: 10.1182/blood-2011-10-387332. Epub 2012 Mar 16. Blood. 2012. PMID: 22427203 Free PMC article.

9

Inflammation-mediated notch signaling skews fanconi anemia hematopoietic stem cell differentiation.

Du W, Amarachintha S, Sipple J, Schick J, Steinbrecher K, Pang Q. Du W, et al. Among authors: sipple j. J Immunol. 2013 Sep 1;191(5):2806-17. doi: 10.4049/jimmunol.1203474. Epub 2013 Aug 7. J Immunol. 2013. PMID: 23926327 Free PMC article.

10

Overexpression of IL-3Rα on CD34+CD38- stem cells defines leukemia-initiating cells in Fanconi anemia AML.

Du W, Li XE, Sipple J, Pang Q. Du W, et al. Among authors: sipple j. Blood. 2011 Apr 21;117(16):4243-52. doi: 10.1182/blood-2010-09-309179. Epub 2011 Feb 17. Blood. 2011. PMID: 21330473 Free PMC article.

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