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De novo design of self-assembling foldamers that inhibit heparin-protein interactions.
Montalvo GL, Zhang Y, Young TM, Costanzo MJ, Freeman KB, Wang J, Clements DJ, Magavern E, Kavash RW, Scott RW, Liu D, Degrado WF. Montalvo GL, et al. Among authors: scott rw. ACS Chem Biol. 2014 Apr 18;9(4):967-75. doi: 10.1021/cb500026x. Epub 2014 Feb 11. ACS Chem Biol. 2014. PMID: 24491145 Free PMC article.
Antibacterial mechanism of action of arylamide foldamers.
Mensa B, Kim YH, Choi S, Scott R, Caputo GA, DeGrado WF. Mensa B, et al. Antimicrob Agents Chemother. 2011 Nov;55(11):5043-53. doi: 10.1128/AAC.05009-11. Epub 2011 Aug 15. Antimicrob Agents Chemother. 2011. PMID: 21844313 Free PMC article.
Platelet factor 4 activity against P. falciparum and its translation to nonpeptidic mimics as antimalarials.
Love MS, Millholland MG, Mishra S, Kulkarni S, Freeman KB, Pan W, Kavash RW, Costanzo MJ, Jo H, Daly TM, Williams DR, Kowalska MA, Bergman LW, Poncz M, DeGrado WF, Sinnis P, Scott RW, Greenbaum DC. Love MS, et al. Among authors: scott rw. Cell Host Microbe. 2012 Dec 13;12(6):815-23. doi: 10.1016/j.chom.2012.10.017. Cell Host Microbe. 2012. PMID: 23245326 Free PMC article.
Acinetobacter baumannii OxPhos inhibitors as selective anti-infective agents.
Rubin H, Selwood T, Yano T, Weaver DG, Loughran HM, Costanzo MJ, Scott RW, Wrobel JE, Freeman KB, Reitz AB. Rubin H, et al. Among authors: scott rw. Bioorg Med Chem Lett. 2015 Jan 15;25(2):378-83. doi: 10.1016/j.bmcl.2014.11.020. Epub 2014 Nov 22. Bioorg Med Chem Lett. 2015. PMID: 25496770
De novo designed synthetic mimics of antimicrobial peptides.
Scott RW, DeGrado WF, Tew GN. Scott RW, et al. Curr Opin Biotechnol. 2008 Dec;19(6):620-7. doi: 10.1016/j.copbio.2008.10.013. Epub 2008 Nov 17. Curr Opin Biotechnol. 2008. PMID: 18996193 Free PMC article. Review.
227 results