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A Fluorogenic Disaccharide Substrate for α-Mannosidases Enables High-Throughput Screening and Identification of an Inhibitor of the GH92 Virulence Factor from Streptococcus pneumoniae.
Bhosale S, Deen MC, Proceviat C, Hettle A, Winter DK, Brockerman J, Levene M, Bennet AJ, Spino C, Boraston AB, Vocadlo DJ. Bhosale S, et al. Among authors: vocadlo dj. ACS Chem Biol. 2023 Aug 18;18(8):1730-1737. doi: 10.1021/acschembio.3c00053. Epub 2023 Aug 2. ACS Chem Biol. 2023. PMID: 37531094
Mechanistic insights into glycosidase chemistry.
Vocadlo DJ, Davies GJ. Vocadlo DJ, et al. Curr Opin Chem Biol. 2008 Oct;12(5):539-55. doi: 10.1016/j.cbpa.2008.05.010. Curr Opin Chem Biol. 2008. PMID: 18558099 Review.
Structural snapshots of the reaction coordinate for O-GlcNAc transferase.
Lazarus MB, Jiang J, Gloster TM, Zandberg WF, Whitworth GE, Vocadlo DJ, Walker S. Lazarus MB, et al. Among authors: vocadlo dj. Nat Chem Biol. 2012 Dec;8(12):966-8. doi: 10.1038/nchembio.1109. Epub 2012 Oct 28. Nat Chem Biol. 2012. PMID: 23103939 Free PMC article.
185 results