Willuda J - Search Results

1

Evaluation of human pancreatic RNase as effector molecule in a therapeutic antibody platform.

Schirrmann T, Frenzel A, Linden L, Stelte-Ludwig B, Willuda J, Harrenga A, Dübel S, Müller-Tiemann B, Trautwein M. Schirrmann T, et al. Among authors: willuda j. MAbs. 2014 Mar-Apr;6(2):367-80. doi: 10.4161/mabs.27830. Epub 2014 Jan 15. MAbs. 2014. PMID: 24492302 Free PMC article.

2

Preclinical Antitumor Efficacy of BAY 1129980-a Novel Auristatin-Based Anti-C4.4A (LYPD3) Antibody-Drug Conjugate for the Treatment of Non-Small Cell Lung Cancer.

Willuda J, Linden L, Lerchen HG, Kopitz C, Stelte-Ludwig B, Pena C, Lange C, Golfier S, Kneip C, Carrigan PE, Mclean K, Schuhmacher J, von Ahsen O, Müller J, Dittmer F, Beier R, El Sheikh S, Tebbe J, Leder G, Apeler H, Jautelat R, Ziegelbauer K, Kreft B. Willuda J, et al. Mol Cancer Ther. 2017 May;16(5):893-904. doi: 10.1158/1535-7163.MCT-16-0474. Epub 2017 Mar 14. Mol Cancer Ther. 2017. PMID: 28292941

3

Generation of a recombinant oncolytic Newcastle disease virus and expression of a full IgG antibody from two transgenes.

Pühler F, Willuda J, Puhlmann J, Mumberg D, Römer-Oberdörfer A, Beier R. Pühler F, et al. Among authors: willuda j. Gene Ther. 2008 Mar;15(5):371-83. doi: 10.1038/sj.gt.3303095. Epub 2008 Jan 17. Gene Ther. 2008. PMID: 18200068

4

High thermal stability is essential for tumor targeting of antibody fragments: engineering of a humanized anti-epithelial glycoprotein-2 (epithelial cell adhesion molecule) single-chain Fv fragment.

Willuda J, Honegger A, Waibel R, Schubiger PA, Stahel R, Zangemeister-Wittke U, Plückthun A. Willuda J, et al. Cancer Res. 1999 Nov 15;59(22):5758-67. Cancer Res. 1999. PMID: 10582696

5

A recombinant immunotoxin derived from a humanized epithelial cell adhesion molecule-specific single-chain antibody fragment has potent and selective antitumor activity.

Di Paolo C, Willuda J, Kubetzko S, Lauffer I, Tschudi D, Waibel R, Plückthun A, Stahel RA, Zangemeister-Wittke U. Di Paolo C, et al. Among authors: willuda j. Clin Cancer Res. 2003 Jul;9(7):2837-48. Clin Cancer Res. 2003. PMID: 12855664

6

Tumor targeting of mono-, di-, and tetravalent anti-p185(HER-2) miniantibodies multimerized by self-associating peptides.

Willuda J, Kubetzko S, Waibel R, Schubiger PA, Zangemeister-Wittke U, Plückthun A. Willuda J, et al. J Biol Chem. 2001 Apr 27;276(17):14385-92. doi: 10.1074/jbc.M011669200. Epub 2001 Jan 22. J Biol Chem. 2001. PMID: 11278961 Free article.

7

Reliable cloning of functional antibody variable domains from hybridomas and spleen cell repertoires employing a reengineered phage display system.

Krebber A, Bornhauser S, Burmester J, Honegger A, Willuda J, Bosshard HR, Plückthun A. Krebber A, et al. Among authors: willuda j. J Immunol Methods. 1997 Feb 14;201(1):35-55. doi: 10.1016/s0022-1759(96)00208-6. J Immunol Methods. 1997. PMID: 9032408

8

Stable one-step technetium-99m labeling of His-tagged recombinant proteins with a novel Tc(I)-carbonyl complex.

Waibel R, Alberto R, Willuda J, Finnern R, Schibli R, Stichelberger A, Egli A, Abram U, Mach JP, Plückthun A, Schubiger PA. Waibel R, et al. Among authors: willuda j. Nat Biotechnol. 1999 Sep;17(9):897-901. doi: 10.1038/12890. Nat Biotechnol. 1999. PMID: 10471933

9

T cell-mediated elimination of cancer cells by blocking CEACAM6-CEACAM1 interaction.

Pinkert J, Boehm HH, Trautwein M, Doecke WD, Wessel F, Ge Y, Gutierrez EM, Carretero R, Freiberg C, Gritzan U, Luetke-Eversloh M, Golfier S, Von Ahsen O, Volpin V, Sorrentino A, Rathinasamy A, Xydia M, Lohmayer R, Sax J, Nur-Menevse A, Hussein A, Stamova S, Beckmann G, Glueck JM, Schoenfeld D, Weiske J, Zopf D, Offringa R, Kreft B, Beckhove P, Willuda J. Pinkert J, et al. Among authors: willuda j. Oncoimmunology. 2021 Dec 30;11(1):2008110. doi: 10.1080/2162402X.2021.2008110. eCollection 2022. Oncoimmunology. 2021. PMID: 35141051 Free PMC article.

10

A Small Molecule-Drug Conjugate (SMDC) Consisting of a Modified Camptothecin Payload Linked to an α_Vß₃ Binder for the Treatment of Multiple Cancer Types.

Lerchen HG, Stelte-Ludwig B, Kopitz C, Heroult M, Zubov D, Willuda J, Schlange T, Kahnert A, Wong H, Izumi R, Hamdy A. Lerchen HG, et al. Among authors: willuda j. Cancers (Basel). 2022 Jan 13;14(2):391. doi: 10.3390/cancers14020391. Cancers (Basel). 2022. PMID: 35053556 Free PMC article.

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