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Page 1
Differential escape patterns within the dominant HLA-B*57:03-restricted HIV Gag epitope reflect distinct clade-specific functional constraints.
Payne RP, Branch S, Kløverpris H, Matthews PC, Koofhethile CK, Strong T, Adland E, Leitman E, Frater J, Ndung'u T, Hunter E, Haubrich R, Mothe B, Edwards A, Riddell L, Chen F, Harrigan PR, Brumme ZL, Mallal S, John M, Jooste JP, Shapiro R, Deeks SG, Walker BD, Brander C, Landis C, Carlson JM, Prado JG, Goulder PJ. Payne RP, et al. Among authors: frater j. J Virol. 2014 May;88(9):4668-78. doi: 10.1128/JVI.03303-13. Epub 2014 Feb 5. J Virol. 2014. PMID: 24501417 Free PMC article.
Quantifiable cytotoxic T lymphocyte responses and HLA-related risk of progression to AIDS.
Scherer A, Frater J, Oxenius A, Agudelo J, Price DA, Günthard HF, Barnardo M, Perrin L, Hirschel B, Phillips RE, McLean AR; Swiss HIV Cohort Study. Scherer A, et al. Among authors: frater j. Proc Natl Acad Sci U S A. 2004 Aug 17;101(33):12266-70. doi: 10.1073/pnas.0404091101. Epub 2004 Aug 9. Proc Natl Acad Sci U S A. 2004. PMID: 15302942 Free PMC article.
CD8+ T-cell responses to different HIV proteins have discordant associations with viral load.
Kiepiela P, Ngumbela K, Thobakgale C, Ramduth D, Honeyborne I, Moodley E, Reddy S, de Pierres C, Mncube Z, Mkhwanazi N, Bishop K, van der Stok M, Nair K, Khan N, Crawford H, Payne R, Leslie A, Prado J, Prendergast A, Frater J, McCarthy N, Brander C, Learn GH, Nickle D, Rousseau C, Coovadia H, Mullins JI, Heckerman D, Walker BD, Goulder P. Kiepiela P, et al. Among authors: frater j. Nat Med. 2007 Jan;13(1):46-53. doi: 10.1038/nm1520. Epub 2006 Dec 17. Nat Med. 2007. PMID: 17173051
Adaptation of HIV-1 to human leukocyte antigen class I.
Kawashima Y, Pfafferott K, Frater J, Matthews P, Payne R, Addo M, Gatanaga H, Fujiwara M, Hachiya A, Koizumi H, Kuse N, Oka S, Duda A, Prendergast A, Crawford H, Leslie A, Brumme Z, Brumme C, Allen T, Brander C, Kaslow R, Tang J, Hunter E, Allen S, Mulenga J, Branch S, Roach T, John M, Mallal S, Ogwu A, Shapiro R, Prado JG, Fidler S, Weber J, Pybus OG, Klenerman P, Ndung'u T, Phillips R, Heckerman D, Harrigan PR, Walker BD, Takiguchi M, Goulder P. Kawashima Y, et al. Among authors: frater j. Nature. 2009 Apr 2;458(7238):641-5. doi: 10.1038/nature07746. Epub 2009 Feb 25. Nature. 2009. PMID: 19242411 Free PMC article.
Modelling the evolution and spread of HIV immune escape mutants.
Fryer HR, Frater J, Duda A, Roberts MG; SPARTAC Trial Investigators; Phillips RE, McLean AR. Fryer HR, et al. Among authors: frater j. PLoS Pathog. 2010 Nov 18;6(11):e1001196. doi: 10.1371/journal.ppat.1001196. PLoS Pathog. 2010. PMID: 21124991 Free PMC article.
HLA-A*7401-mediated control of HIV viremia is independent of its linkage disequilibrium with HLA-B*5703.
Matthews PC, Adland E, Listgarten J, Leslie A, Mkhwanazi N, Carlson JM, Harndahl M, Stryhn A, Payne RP, Ogwu A, Huang KH, Frater J, Paioni P, Kloverpris H, Jooste P, Goedhals D, van Vuuren C, Steyn D, Riddell L, Chen F, Luzzi G, Balachandran T, Ndung'u T, Buus S, Carrington M, Shapiro R, Heckerman D, Goulder PJ. Matthews PC, et al. Among authors: frater j. J Immunol. 2011 May 15;186(10):5675-86. doi: 10.4049/jimmunol.1003711. Epub 2011 Apr 15. J Immunol. 2011. PMID: 21498667 Free PMC article.
Progression to AIDS in South Africa is associated with both reverting and compensatory viral mutations.
Huang KH, Goedhals D, Carlson JM, Brockman MA, Mishra S, Brumme ZL, Hickling S, Tang CS, Miura T, Seebregts C, Heckerman D, Ndung'u T, Walker B, Klenerman P, Steyn D, Goulder P, Phillips R; Bloemfontein-Oxford Collaborative Group; van Vuuren C, Frater J. Huang KH, et al. Among authors: frater j. PLoS One. 2011 Apr 22;6(4):e19018. doi: 10.1371/journal.pone.0019018. PLoS One. 2011. PMID: 21544209 Free PMC article.
Widespread impact of HLA restriction on immune control and escape pathways of HIV-1.
Carlson JM, Listgarten J, Pfeifer N, Tan V, Kadie C, Walker BD, Ndung'u T, Shapiro R, Frater J, Brumme ZL, Goulder PJ, Heckerman D. Carlson JM, et al. Among authors: frater j. J Virol. 2012 May;86(9):5230-43. doi: 10.1128/JVI.06728-11. Epub 2012 Feb 29. J Virol. 2012. PMID: 22379086 Free PMC article.
278 results