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Page 1
Differential escape patterns within the dominant HLA-B*57:03-restricted HIV Gag epitope reflect distinct clade-specific functional constraints.
Payne RP, Branch S, Kløverpris H, Matthews PC, Koofhethile CK, Strong T, Adland E, Leitman E, Frater J, Ndung'u T, Hunter E, Haubrich R, Mothe B, Edwards A, Riddell L, Chen F, Harrigan PR, Brumme ZL, Mallal S, John M, Jooste JP, Shapiro R, Deeks SG, Walker BD, Brander C, Landis C, Carlson JM, Prado JG, Goulder PJ. Payne RP, et al. Among authors: koofhethile ck. J Virol. 2014 May;88(9):4668-78. doi: 10.1128/JVI.03303-13. Epub 2014 Feb 5. J Virol. 2014. PMID: 24501417 Free PMC article.
CD8+ TCR Bias and Immunodominance in HIV-1 Infection.
Kløverpris HN, McGregor R, McLaren JE, Ladell K, Harndahl M, Stryhn A, Carlson JM, Koofhethile C, Gerritsen B, Keşmir C, Chen F, Riddell L, Luzzi G, Leslie A, Walker BD, Ndung'u T, Buus S, Price DA, Goulder PJ. Kløverpris HN, et al. J Immunol. 2015 Jun 1;194(11):5329-45. doi: 10.4049/jimmunol.1400854. Epub 2015 Apr 24. J Immunol. 2015. PMID: 25911754 Free PMC article.
The HIV-2 proviral landscape is dominated by defective proviruses.
Koofhethile CK, Gao C, Chang C, Lian X, Shapiro R, Yu XG, Lichterfeld M, Kanki PJ. Koofhethile CK, et al. AIDS. 2024 Mar 1;38(3):309-316. doi: 10.1097/QAD.0000000000003776. Epub 2023 Nov 22. AIDS. 2024. PMID: 37916471 Free PMC article.
Undetectable proviral deoxyribonucleic acid in an adolescent perinatally infected with human immunodeficiency virus-1C and on long-term antiretroviral therapy resulted in viral rebound following antiretroviral therapy termination: A case report with implications for clinical care.
Koofhethile CK, Moyo S, Kotokwe KP, Mokgethi P, Muchoba L, Mokgweetsi S, Gaolathe T, Makhema J, Shapiro R, Lockman S, Kanki P, Essex M, Gaseitsiwe S, de Oliveira T, Novitsky V. Koofhethile CK, et al. Medicine (Baltimore). 2019 Nov;98(47):e18014. doi: 10.1097/MD.0000000000018014. Medicine (Baltimore). 2019. PMID: 31764816 Free PMC article.
Detection of Inducible Replication-Competent HIV-1 Subtype C Provirus Despite Long-Term Antiretroviral Treatment in Perinatally Infected Adolescents in Botswana.
Koofhethile CK, Moyo S, Kotokwe KP, Chang C, Mokgethi P, Muchoba L, Mokgweetsi S, Makhema J, Lockman S, Gaseitsiwe S, de Oliveira T, Essex M, Shapiro R, Kanki P, Novitsky V. Koofhethile CK, et al. AIDS Res Hum Retroviruses. 2021 Jan;37(1):16-23. doi: 10.1089/AID.2020.0097. Epub 2020 Oct 19. AIDS Res Hum Retroviruses. 2021. PMID: 32935556 Free PMC article.
Low prevalence of archived integrase strand transfer inhibitors resistance associated mutations in Botswana before the roll out of dolutegravir based first line antiretroviral therapy.
Maruapula D, Ditshwanelo D, Pema MN, Bareng OT, Choga WT, Moraka NO, Mokgethi PT, Seatla KK, Koofhethile CK, Zuze BJ, Gaolathe T, Pretorius-Holme M, Lebani K, Makhema J, Novitsky V, Shapiro R, Lockman S, Moyo S, Gaseitsiwe S. Maruapula D, et al. Among authors: koofhethile ck. Front Microbiol. 2024 Oct 24;15:1482348. doi: 10.3389/fmicb.2024.1482348. eCollection 2024. Front Microbiol. 2024. PMID: 39512940 Free PMC article.
17 results