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Page 1
A microbiological assessment of novel nitrofuranylamides as anti-tuberculosis agents.
Hurdle JG, Lee RB, Budha NR, Carson EI, Qi J, Scherman MS, Cho SH, McNeil MR, Lenaerts AJ, Franzblau SG, Meibohm B, Lee RE. Hurdle JG, et al. Among authors: mcneil mr. J Antimicrob Chemother. 2008 Nov;62(5):1037-45. doi: 10.1093/jac/dkn307. Epub 2008 Aug 7. J Antimicrob Chemother. 2008. PMID: 18693235 Free PMC article.
Antitubercular nitrofuran isoxazolines with improved pharmacokinetic properties.
Rakesh, Bruhn D, Madhura DB, Maddox M, Lee RB, Trivedi A, Yang L, Scherman MS, Gilliland JC, Gruppo V, McNeil MR, Lenaerts AJ, Meibohm B, Lee RE. Rakesh, et al. Among authors: mcneil mr. Bioorg Med Chem. 2012 Oct 15;20(20):6063-72. doi: 10.1016/j.bmc.2012.08.023. Epub 2012 Aug 28. Bioorg Med Chem. 2012. PMID: 22995771 Free PMC article.
Design, synthesis and anti-tuberculosis activity of 1-adamantyl-3-heteroaryl ureas with improved in vitro pharmacokinetic properties.
North EJ, Scherman MS, Bruhn DF, Scarborough JS, Maddox MM, Jones V, Grzegorzewicz A, Yang L, Hess T, Morisseau C, Jackson M, McNeil MR, Lee RE. North EJ, et al. Among authors: mcneil mr. Bioorg Med Chem. 2013 May 1;21(9):2587-99. doi: 10.1016/j.bmc.2013.02.028. Epub 2013 Feb 26. Bioorg Med Chem. 2013. PMID: 23498915 Free PMC article.
Spectinamides: a new class of semisynthetic antituberculosis agents that overcome native drug efflux.
Lee RE, Hurdle JG, Liu J, Bruhn DF, Matt T, Scherman MS, Vaddady PK, Zheng Z, Qi J, Akbergenov R, Das S, Madhura DB, Rathi C, Trivedi A, Villellas C, Lee RB, Rakesh, Waidyarachchi SL, Sun D, McNeil MR, Ainsa JA, Boshoff HI, Gonzalez-Juarrero M, Meibohm B, Böttger EC, Lenaerts AJ. Lee RE, et al. Among authors: mcneil mr. Nat Med. 2014 Feb;20(2):152-158. doi: 10.1038/nm.3458. Epub 2014 Jan 26. Nat Med. 2014. PMID: 24464186 Free PMC article.
Drug targeting Mycobacterium tuberculosis cell wall synthesis: development of a microtiter plate-based screen for UDP-galactopyranose mutase and identification of an inhibitor from a uridine-based library.
Scherman MS, Winans KA, Stern RJ, Jones V, Bertozzi CR, McNeil MR. Scherman MS, et al. Among authors: mcneil mr. Antimicrob Agents Chemother. 2003 Jan;47(1):378-82. doi: 10.1128/AAC.47.1.378-382.2003. Antimicrob Agents Chemother. 2003. PMID: 12499218 Free PMC article.
The structure-activity relationship of urea derivatives as anti-tuberculosis agents.
Brown JR, North EJ, Hurdle JG, Morisseau C, Scarborough JS, Sun D, Korduláková J, Scherman MS, Jones V, Grzegorzewicz A, Crew RM, Jackson M, McNeil MR, Lee RE. Brown JR, et al. Among authors: mcneil mr. Bioorg Med Chem. 2011 Sep 15;19(18):5585-95. doi: 10.1016/j.bmc.2011.07.034. Epub 2011 Jul 24. Bioorg Med Chem. 2011. PMID: 21840723 Free PMC article.
Inhibition of mycolic acid transport across the Mycobacterium tuberculosis plasma membrane.
Grzegorzewicz AE, Pham H, Gundi VA, Scherman MS, North EJ, Hess T, Jones V, Gruppo V, Born SE, Korduláková J, Chavadi SS, Morisseau C, Lenaerts AJ, Lee RE, McNeil MR, Jackson M. Grzegorzewicz AE, et al. Among authors: mcneil mr. Nat Chem Biol. 2012 Feb 19;8(4):334-41. doi: 10.1038/nchembio.794. Nat Chem Biol. 2012. PMID: 22344175 Free PMC article.
225 results