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DAF-16/FoxO directly regulates an atypical AMP-activated protein kinase gamma isoform to mediate the effects of insulin/IGF-1 signaling on aging in Caenorhabditis elegans.
Tullet JM, Araiz C, Sanders MJ, Au C, Benedetto A, Papatheodorou I, Clark E, Schmeisser K, Jones D, Schuster EF, Thornton JM, Gems D. Tullet JM, et al. Among authors: au c. PLoS Genet. 2014 Feb 6;10(2):e1004109. doi: 10.1371/journal.pgen.1004109. eCollection 2014 Feb. PLoS Genet. 2014. PMID: 24516399 Free PMC article.
C. elegans Eats Its Own Intestine to Make Yolk Leading to Multiple Senescent Pathologies.
Ezcurra M, Benedetto A, Sornda T, Gilliat AF, Au C, Zhang Q, van Schelt S, Petrache AL, Wang H, de la Guardia Y, Bar-Nun S, Tyler E, Wakelam MJ, Gems D. Ezcurra M, et al. Among authors: au c. Curr Biol. 2018 Aug 20;28(16):2544-2556.e5. doi: 10.1016/j.cub.2018.06.035. Epub 2018 Aug 9. Curr Biol. 2018. PMID: 30100339 Free PMC article.
Absence of effects of Sir2 overexpression on lifespan in C. elegans and Drosophila.
Burnett C, Valentini S, Cabreiro F, Goss M, Somogyvári M, Piper MD, Hoddinott M, Sutphin GL, Leko V, McElwee JJ, Vazquez-Manrique RP, Orfila AM, Ackerman D, Au C, Vinti G, Riesen M, Howard K, Neri C, Bedalov A, Kaeberlein M, Soti C, Partridge L, Gems D. Burnett C, et al. Among authors: au c. Nature. 2011 Sep 21;477(7365):482-5. doi: 10.1038/nature10296. Nature. 2011. PMID: 21938067 Free PMC article.
557 results