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DAF-16/FoxO directly regulates an atypical AMP-activated protein kinase gamma isoform to mediate the effects of insulin/IGF-1 signaling on aging in Caenorhabditis elegans.
Tullet JM, Araiz C, Sanders MJ, Au C, Benedetto A, Papatheodorou I, Clark E, Schmeisser K, Jones D, Schuster EF, Thornton JM, Gems D. Tullet JM, et al. Among authors: sanders mj. PLoS Genet. 2014 Feb 6;10(2):e1004109. doi: 10.1371/journal.pgen.1004109. eCollection 2014 Feb. PLoS Genet. 2014. PMID: 24516399 Free PMC article.
AMP-activated protein kinase: nature's energy sensor.
Carling D, Mayer FV, Sanders MJ, Gamblin SJ. Carling D, et al. Among authors: sanders mj. Nat Chem Biol. 2011 Jul 18;7(8):512-8. doi: 10.1038/nchembio.610. Nat Chem Biol. 2011. PMID: 21769098 Review.
ADP regulates SNF1, the Saccharomyces cerevisiae homolog of AMP-activated protein kinase.
Mayer FV, Heath R, Underwood E, Sanders MJ, Carmena D, McCartney RR, Leiper FC, Xiao B, Jing C, Walker PA, Haire LF, Ogrodowicz R, Martin SR, Schmidt MC, Gamblin SJ, Carling D. Mayer FV, et al. Among authors: sanders mj. Cell Metab. 2011 Nov 2;14(5):707-14. doi: 10.1016/j.cmet.2011.09.009. Epub 2011 Oct 20. Cell Metab. 2011. PMID: 22019086 Free PMC article.
AMP-activated protein kinase: new regulation, new roles?
Carling D, Thornton C, Woods A, Sanders MJ. Carling D, et al. Among authors: sanders mj. Biochem J. 2012 Jul 1;445(1):11-27. doi: 10.1042/BJ20120546. Biochem J. 2012. PMID: 22702974 Review.
Structure of mammalian AMPK and its regulation by ADP.
Xiao B, Sanders MJ, Underwood E, Heath R, Mayer FV, Carmena D, Jing C, Walker PA, Eccleston JF, Haire LF, Saiu P, Howell SA, Aasland R, Martin SR, Carling D, Gamblin SJ. Xiao B, et al. Among authors: sanders mj. Nature. 2011 Apr 14;472(7342):230-3. doi: 10.1038/nature09932. Epub 2011 Mar 13. Nature. 2011. PMID: 21399626 Free PMC article.
Structural basis of AMPK regulation by small molecule activators.
Xiao B, Sanders MJ, Carmena D, Bright NJ, Haire LF, Underwood E, Patel BR, Heath RB, Walker PA, Hallen S, Giordanetto F, Martin SR, Carling D, Gamblin SJ. Xiao B, et al. Among authors: sanders mj. Nat Commun. 2013;4:3017. doi: 10.1038/ncomms4017. Nat Commun. 2013. PMID: 24352254 Free PMC article.
107 results