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The RhoGEF GEF-H1 is required for oncogenic RAS signaling via KSR-1.
Cullis J, Meiri D, Sandi MJ, Radulovich N, Kent OA, Medrano M, Mokady D, Normand J, Larose J, Marcotte R, Marshall CB, Ikura M, Ketela T, Moffat J, Neel BG, Gingras AC, Tsao MS, Rottapel R. Cullis J, et al. Among authors: gingras ac. Cancer Cell. 2014 Feb 10;25(2):181-95. doi: 10.1016/j.ccr.2014.01.025. Cancer Cell. 2014. PMID: 24525234 Free article.
A lentiviral functional proteomics approach identifies chromatin remodeling complexes important for the induction of pluripotency.
Mak AB, Ni Z, Hewel JA, Chen GI, Zhong G, Karamboulas K, Blakely K, Smiley S, Marcon E, Roudeva D, Li J, Olsen JB, Wan C, Punna T, Isserlin R, Chetyrkin S, Gingras AC, Emili A, Greenblatt J, Moffat J. Mak AB, et al. Among authors: gingras ac. Mol Cell Proteomics. 2010 May;9(5):811-23. doi: 10.1074/mcp.M000002-MCP201. Epub 2010 Mar 19. Mol Cell Proteomics. 2010. PMID: 20305087 Free PMC article.
A Dynamic Protein Interaction Landscape of the Human Centrosome-Cilium Interface.
Gupta GD, Coyaud É, Gonçalves J, Mojarad BA, Liu Y, Wu Q, Gheiratmand L, Comartin D, Tkach JM, Cheung SW, Bashkurov M, Hasegan M, Knight JD, Lin ZY, Schueler M, Hildebrandt F, Moffat J, Gingras AC, Raught B, Pelletier L. Gupta GD, et al. Among authors: gingras ac. Cell. 2015 Dec 3;163(6):1484-99. doi: 10.1016/j.cell.2015.10.065. Cell. 2015. PMID: 26638075 Free PMC article.
A Global Analysis of the Receptor Tyrosine Kinase-Protein Phosphatase Interactome.
Yao Z, Darowski K, St-Denis N, Wong V, Offensperger F, Villedieu A, Amin S, Malty R, Aoki H, Guo H, Xu Y, Iorio C, Kotlyar M, Emili A, Jurisica I, Neel BG, Babu M, Gingras AC, Stagljar I. Yao Z, et al. Among authors: gingras ac. Mol Cell. 2017 Jan 19;65(2):347-360. doi: 10.1016/j.molcel.2016.12.004. Epub 2017 Jan 5. Mol Cell. 2017. PMID: 28065597 Free PMC article.
Evolution of AF6-RAS association and its implications in mixed-lineage leukemia.
Smith MJ, Ottoni E, Ishiyama N, Goudreault M, Haman A, Meyer C, Tucholska M, Gasmi-Seabrook G, Menezes S, Laister RC, Minden MD, Marschalek R, Gingras AC, Hoang T, Ikura M. Smith MJ, et al. Among authors: gingras ac. Nat Commun. 2017 Oct 23;8(1):1099. doi: 10.1038/s41467-017-01326-5. Nat Commun. 2017. PMID: 29062045 Free PMC article.
MARK3-mediated phosphorylation of ARHGEF2 couples microtubules to the actin cytoskeleton to establish cell polarity.
Sandí MJ, Marshall CB, Balan M, Coyaud É, Zhou M, Monson DM, Ishiyama N, Chandrakumar AA, La Rose J, Couzens AL, Gingras AC, Raught B, Xu W, Ikura M, Morrison DK, Rottapel R. Sandí MJ, et al. Among authors: gingras ac. Sci Signal. 2017 Oct 31;10(503):eaan3286. doi: 10.1126/scisignal.aan3286. Sci Signal. 2017. PMID: 29089450 Free PMC article.
Genome-wide CRISPR-Cas9 Interrogation of Splicing Networks Reveals a Mechanism for Recognition of Autism-Misregulated Neuronal Microexons.
Gonatopoulos-Pournatzis T, Wu M, Braunschweig U, Roth J, Han H, Best AJ, Raj B, Aregger M, O'Hanlon D, Ellis JD, Calarco JA, Moffat J, Gingras AC, Blencowe BJ. Gonatopoulos-Pournatzis T, et al. Among authors: gingras ac. Mol Cell. 2018 Nov 1;72(3):510-524.e12. doi: 10.1016/j.molcel.2018.10.008. Mol Cell. 2018. PMID: 30388412 Free article.
391 results