KN-93, a specific inhibitor of CaMKII inhibits human hepatic stellate cell proliferation in vitro.
An P, Zhu JY, Yang Y, Lv P, Tian YH, Chen MK, Luo HS.
An P, et al.
World J Gastroenterol. 2007 Mar 7;13(9):1445-8. doi: 10.3748/wjg.v13.i9.1445.
World J Gastroenterol. 2007.
PMID: 17457979
Free PMC article.
RESULTS: KN-93 (5-50 micromol/L) decreased the proliferation of human hepatic stellate cells in a dose-dependent manner from 81.76% (81.76% +/- 2.58% vs 96.63% +/- 2.69%, P < 0.05) to 27.15% (27.15% +/- 2.86% vs 96.59% +/- 2.44%, P < 0.01) after 24 h treatment
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RESULTS: KN-93 (5-50 micromol/L) decreased the proliferation of human hepatic stellate cells in a dose-dependent manner from 81.76% (81.76% …