Kastan MB - Search Results

1

Rad17 recruits the MRE11-RAD50-NBS1 complex to regulate the cellular response to DNA double-strand breaks.

Wang Q, Goldstein M, Alexander P, Wakeman TP, Sun T, Feng J, Lou Z, Kastan MB, Wang XF. Wang Q, et al. Among authors: kastan mb. EMBO J. 2014 Apr 16;33(8):862-77. doi: 10.1002/embj.201386064. Epub 2014 Feb 16. EMBO J. 2014. PMID: 24534091 Free PMC article.

2

Repair versus Checkpoint Functions of BRCA1 Are Differentially Regulated by Site of Chromatin Binding.

Goldstein M, Kastan MB. Goldstein M, et al. Among authors: kastan mb. Cancer Res. 2015 Jul 1;75(13):2699-707. doi: 10.1158/0008-5472.CAN-15-0400. Epub 2015 May 4. Cancer Res. 2015. PMID: 25939603 Free PMC article.

3

The DNA damage response: implications for tumor responses to radiation and chemotherapy.

Goldstein M, Kastan MB. Goldstein M, et al. Among authors: kastan mb. Annu Rev Med. 2015;66:129-43. doi: 10.1146/annurev-med-081313-121208. Epub 2014 Nov 24. Annu Rev Med. 2015. PMID: 25423595 Review.

4

The scaffold protein WRAP53β orchestrates the ubiquitin response critical for DNA double-strand break repair.

Henriksson S, Rassoolzadeh H, Hedström E, Coucoravas C, Julner A, Goldstein M, Imreh G, Zhivotovsky B, Kastan MB, Helleday T, Farnebo M. Henriksson S, et al. Among authors: kastan mb. Genes Dev. 2014 Dec 15;28(24):2726-38. doi: 10.1101/gad.246546.114. Genes Dev. 2014. PMID: 25512560 Free PMC article.

5

Nucleolin mediates nucleosome disruption critical for DNA double-strand break repair.

Goldstein M, Derheimer FA, Tait-Mulder J, Kastan MB. Goldstein M, et al. Among authors: kastan mb. Proc Natl Acad Sci U S A. 2013 Oct 15;110(42):16874-9. doi: 10.1073/pnas.1306160110. Epub 2013 Sep 30. Proc Natl Acad Sci U S A. 2013. PMID: 24082117 Free PMC article.

6

Inactivation of the human papillomavirus E6 or E7 gene in cervical carcinoma cells by using a bacterial CRISPR/Cas RNA-guided endonuclease.

Kennedy EM, Kornepati AV, Goldstein M, Bogerd HP, Poling BC, Whisnant AW, Kastan MB, Cullen BR. Kennedy EM, et al. Among authors: kastan mb. J Virol. 2014 Oct;88(20):11965-72. doi: 10.1128/JVI.01879-14. Epub 2014 Aug 6. J Virol. 2014. PMID: 25100830 Free PMC article.

7

Self-inflicted DNA double-strand breaks sustain tumorigenicity and stemness of cancer cells.

Liu X, Li F, Huang Q, Zhang Z, Zhou L, Deng Y, Zhou M, Fleenor DE, Wang H, Kastan MB, Li CY. Liu X, et al. Among authors: kastan mb. Cell Res. 2017 Jun;27(6):764-783. doi: 10.1038/cr.2017.41. Epub 2017 Mar 24. Cell Res. 2017. PMID: 28337983 Free PMC article.

8

Chromatin perturbations during the DNA damage response in higher eukaryotes.

Bakkenist CJ, Kastan MB. Bakkenist CJ, et al. Among authors: kastan mb. DNA Repair (Amst). 2015 Dec;36:8-12. doi: 10.1016/j.dnarep.2015.09.002. Epub 2015 Sep 9. DNA Repair (Amst). 2015. PMID: 26391293 Free PMC article. Review.

9

The Rad50S allele promotes ATM-dependent DNA damage responses and suppresses ATM deficiency: implications for the Mre11 complex as a DNA damage sensor.

Morales M, Theunissen JW, Kim CF, Kitagawa R, Kastan MB, Petrini JH. Morales M, et al. Among authors: kastan mb. Genes Dev. 2005 Dec 15;19(24):3043-54. doi: 10.1101/gad.1373705. Genes Dev. 2005. PMID: 16357220 Free PMC article.

10

Spatial organization of the mammalian genome surveillance machinery in response to DNA strand breaks.

Bekker-Jensen S, Lukas C, Kitagawa R, Melander F, Kastan MB, Bartek J, Lukas J. Bekker-Jensen S, et al. Among authors: kastan mb. J Cell Biol. 2006 Apr 24;173(2):195-206. doi: 10.1083/jcb.200510130. Epub 2006 Apr 17. J Cell Biol. 2006. PMID: 16618811 Free PMC article.

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