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Benzimidazole-based compounds kill Mycobacterium tuberculosis.
Gong Y, Somersan Karakaya S, Guo X, Zheng P, Gold B, Ma Y, Little D, Roberts J, Warrier T, Jiang X, Pingle M, Nathan CF, Liu G. Gong Y, et al. Among authors: somersan karakaya s. Eur J Med Chem. 2014 Mar 21;75:336-53. doi: 10.1016/j.ejmech.2014.01.039. Epub 2014 Jan 31. Eur J Med Chem. 2014. PMID: 24556148
Rapid, Semiquantitative Assay To Discriminate among Compounds with Activity against Replicating or Nonreplicating Mycobacterium tuberculosis.
Gold B, Roberts J, Ling Y, Quezada LL, Glasheen J, Ballinger E, Somersan-Karakaya S, Warrier T, Warren JD, Nathan C. Gold B, et al. Among authors: somersan karakaya s. Antimicrob Agents Chemother. 2015 Oct;59(10):6521-38. doi: 10.1128/AAC.00803-15. Epub 2015 Aug 3. Antimicrob Agents Chemother. 2015. PMID: 26239979 Free PMC article.
N-methylation of a bactericidal compound as a resistance mechanism in Mycobacterium tuberculosis.
Warrier T, Kapilashrami K, Argyrou A, Ioerger TR, Little D, Murphy KC, Nandakumar M, Park S, Gold B, Mi J, Zhang T, Meiler E, Rees M, Somersan-Karakaya S, Porras-De Francisco E, Martinez-Hoyos M, Burns-Huang K, Roberts J, Ling Y, Rhee KY, Mendoza-Losana A, Luo M, Nathan CF. Warrier T, et al. Among authors: somersan karakaya s. Proc Natl Acad Sci U S A. 2016 Aug 2;113(31):E4523-30. doi: 10.1073/pnas.1606590113. Epub 2016 Jul 18. Proc Natl Acad Sci U S A. 2016. PMID: 27432954 Free PMC article.
Identification of Novel Anti-mycobacterial Compounds by Screening a Pharmaceutical Small-Molecule Library against Nonreplicating Mycobacterium tuberculosis.
Warrier T, Martinez-Hoyos M, Marin-Amieva M, Colmenarejo G, Porras-De Francisco E, Alvarez-Pedraglio AI, Fraile-Gabaldon MT, Torres-Gomez PA, Lopez-Quezada L, Gold B, Roberts J, Ling Y, Somersan-Karakaya S, Little D, Cammack N, Nathan C, Mendoza-Losana A. Warrier T, et al. Among authors: somersan karakaya s. ACS Infect Dis. 2015 Dec 11;1(12):580-5. doi: 10.1021/acsinfecdis.5b00025. Epub 2015 Jun 22. ACS Infect Dis. 2015. PMID: 27623055 Free article.
Rifamycin action on RNA polymerase in antibiotic-tolerant Mycobacterium tuberculosis results in differentially detectable populations.
Saito K, Warrier T, Somersan-Karakaya S, Kaminski L, Mi J, Jiang X, Park S, Shigyo K, Gold B, Roberts J, Weber E, Jacobs WR Jr, Nathan CF. Saito K, et al. Among authors: somersan karakaya s. Proc Natl Acad Sci U S A. 2017 Jun 13;114(24):E4832-E4840. doi: 10.1073/pnas.1705385114. Epub 2017 May 30. Proc Natl Acad Sci U S A. 2017. PMID: 28559332 Free PMC article.
Identification of a Mycothiol-Dependent Nitroreductase from Mycobacterium tuberculosis.
Negri A, Javidnia P, Mu R, Zhang X, Vendome J, Gold B, Roberts J, Barman D, Ioerger T, Sacchettini JC, Jiang X, Burns-Huang K, Warrier T, Ling Y, Warren JD, Oren DA, Beuming T, Wang H, Wu J, Li H, Rhee KY, Nathan CF, Liu G, Somersan-Karakaya S. Negri A, et al. Among authors: somersan karakaya s. ACS Infect Dis. 2018 May 11;4(5):771-787. doi: 10.1021/acsinfecdis.7b00111. Epub 2018 Feb 21. ACS Infect Dis. 2018. PMID: 29465985 Free PMC article.
Dual-Pharmacophore Pyrithione-Containing Cephalosporins Kill Both Replicating and Nonreplicating Mycobacterium tuberculosis.
Lopez Quezada L, Li K, McDonald SL, Nguyen Q, Perkowski AJ, Pharr CW, Gold B, Roberts J, McAulay K, Saito K, Somersan Karakaya S, Javidnia PE, Porras de Francisco E, Amieva MM, Dı Az SP, Mendoza Losana A, Zimmerman M, Liang HH, Zhang J, Dartois V, Sans S, Lagrange S, Goullieux L, Roubert C, Nathan C, Aubé J. Lopez Quezada L, et al. Among authors: somersan karakaya s. ACS Infect Dis. 2019 Aug 9;5(8):1433-1445. doi: 10.1021/acsinfecdis.9b00112. Epub 2019 Jun 11. ACS Infect Dis. 2019. PMID: 31184461 Free PMC article.
26 results