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Methylene blue upregulates Nrf2/ARE genes and prevents tau-related neurotoxicity.
Stack C, Jainuddin S, Elipenahli C, Gerges M, Starkova N, Starkov AA, Jové M, Portero-Otin M, Launay N, Pujol A, Kaidery NA, Thomas B, Tampellini D, Beal MF, Dumont M. Stack C, et al. Among authors: dumont m. Hum Mol Genet. 2014 Jul 15;23(14):3716-32. doi: 10.1093/hmg/ddu080. Epub 2014 Feb 20. Hum Mol Genet. 2014. PMID: 24556215 Free PMC article.
Benfotiamine treatment activates the Nrf2/ARE pathway and is neuroprotective in a transgenic mouse model of tauopathy.
Tapias V, Jainuddin S, Ahuja M, Stack C, Elipenahli C, Vignisse J, Gerges M, Starkova N, Xu H, Starkov AA, Bettendorff L, Hushpulian DM, Smirnova NA, Gazaryan IG, Kaidery NA, Wakade S, Calingasan NY, Thomas B, Gibson GE, Dumont M, Beal MF. Tapias V, et al. Among authors: dumont m. Hum Mol Genet. 2018 Aug 15;27(16):2874-2892. doi: 10.1093/hmg/ddy201. Hum Mol Genet. 2018. PMID: 29860433 Free PMC article.
Triterpenoids CDDO-ethyl amide and CDDO-trifluoroethyl amide improve the behavioral phenotype and brain pathology in a transgenic mouse model of Huntington's disease.
Stack C, Ho D, Wille E, Calingasan NY, Williams C, Liby K, Sporn M, Dumont M, Beal MF. Stack C, et al. Among authors: dumont m. Free Radic Biol Med. 2010 Jul 15;49(2):147-58. doi: 10.1016/j.freeradbiomed.2010.03.017. Epub 2010 Mar 23. Free Radic Biol Med. 2010. PMID: 20338236 Free PMC article.
1,042 results