Cowen LE - Search Results

1

Progress and prospects for targeting Hsp90 to treat fungal infections.

Veri A, Cowen LE. Veri A, et al. Among authors: cowen le. Parasitology. 2014 Aug;141(9):1127-37. doi: 10.1017/S0031182013002072. Epub 2014 Feb 20. Parasitology. 2014. PMID: 24560124

2

The evolution of fungal drug resistance: modulating the trajectory from genotype to phenotype.

Cowen LE. Cowen LE. Nat Rev Microbiol. 2008 Mar;6(3):187-98. doi: 10.1038/nrmicro1835. Nat Rev Microbiol. 2008. PMID: 18246082 Review.

3

Harnessing Hsp90 function as a powerful, broadly effective therapeutic strategy for fungal infectious disease.

Cowen LE, Singh SD, Köhler JR, Collins C, Zaas AK, Schell WA, Aziz H, Mylonakis E, Perfect JR, Whitesell L, Lindquist S. Cowen LE, et al. Proc Natl Acad Sci U S A. 2009 Feb 24;106(8):2818-23. doi: 10.1073/pnas.0813394106. Epub 2009 Feb 5. Proc Natl Acad Sci U S A. 2009. PMID: 19196973 Free PMC article.

4

Hsp90 orchestrates temperature-dependent Candida albicans morphogenesis via Ras1-PKA signaling.

Shapiro RS, Uppuluri P, Zaas AK, Collins C, Senn H, Perfect JR, Heitman J, Cowen LE. Shapiro RS, et al. Among authors: cowen le. Curr Biol. 2009 Apr 28;19(8):621-9. doi: 10.1016/j.cub.2009.03.017. Epub 2009 Mar 26. Curr Biol. 2009. PMID: 19327993 Free PMC article.

5

Metabolic control of antifungal drug resistance.

Robbins N, Collins C, Morhayim J, Cowen LE. Robbins N, et al. Among authors: cowen le. Fungal Genet Biol. 2010 Feb;47(2):81-93. doi: 10.1016/j.fgb.2009.07.004. Epub 2009 Jul 10. Fungal Genet Biol. 2010. PMID: 19595784

6

Hsp90 governs echinocandin resistance in the pathogenic yeast Candida albicans via calcineurin.

Singh SD, Robbins N, Zaas AK, Schell WA, Perfect JR, Cowen LE. Singh SD, et al. Among authors: cowen le. PLoS Pathog. 2009 Jul;5(7):e1000532. doi: 10.1371/journal.ppat.1000532. Epub 2009 Jul 31. PLoS Pathog. 2009. PMID: 19649312 Free PMC article.

7

Hsp90 orchestrates stress response signaling governing fungal drug resistance.

Cowen LE. Cowen LE. PLoS Pathog. 2009 Aug;5(8):e1000471. doi: 10.1371/journal.ppat.1000471. Epub 2009 Aug 28. PLoS Pathog. 2009. PMID: 19714223 Free PMC article. No abstract available.

8

PKC signaling regulates drug resistance of the fungal pathogen Candida albicans via circuitry comprised of Mkc1, calcineurin, and Hsp90.

LaFayette SL, Collins C, Zaas AK, Schell WA, Betancourt-Quiroz M, Gunatilaka AA, Perfect JR, Cowen LE. LaFayette SL, et al. Among authors: cowen le. PLoS Pathog. 2010 Aug 26;6(8):e1001069. doi: 10.1371/journal.ppat.1001069. PLoS Pathog. 2010. PMID: 20865172 Free PMC article.

9

Coupling temperature sensing and development: Hsp90 regulates morphogenetic signalling in Candida albicans.

Shapiro RS, Cowen L. Shapiro RS, et al. Virulence. 2010 Jan-Feb;1(1):45-8. doi: 10.4161/viru.1.1.10320. Virulence. 2010. PMID: 21178413 Free PMC article. Review.

10

Regulatory circuitry governing fungal development, drug resistance, and disease.

Shapiro RS, Robbins N, Cowen LE. Shapiro RS, et al. Among authors: cowen le. Microbiol Mol Biol Rev. 2011 Jun;75(2):213-67. doi: 10.1128/MMBR.00045-10. Microbiol Mol Biol Rev. 2011. PMID: 21646428 Free PMC article. Review.

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