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Page 1
A DOCK8-WIP-WASp complex links T cell receptors to the actin cytoskeleton.
Janssen E, Tohme M, Hedayat M, Leick M, Kumari S, Ramesh N, Massaad MJ, Ullas S, Azcutia V, Goodnow CC, Randall KL, Qiao Q, Wu H, Al-Herz W, Cox D, Hartwig J, Irvine DJ, Luscinskas FW, Geha RS. Janssen E, et al. Among authors: leick m. J Clin Invest. 2016 Oct 3;126(10):3837-3851. doi: 10.1172/JCI85774. Epub 2016 Sep 6. J Clin Invest. 2016. PMID: 27599296 Free PMC article.
CD70 CAR T cells secreting an anti-CD33/anti-CD3 dual targeting antibody overcome antigen heterogeneity in AML.
Silva H, Martin G, Birocchi F, Wehrli M, Kann MC, Supper VM, Parker A, Graham CE, Bratt AG, Bouffard AA, Donner H, Escobar G, Takei HN, Armstrong A, Goncalves S, Berger TR, Choi BD, Maus MV, Leick MB. Silva H, et al. Among authors: leick mb. Blood. 2024 Nov 21:blood.2023023210. doi: 10.1182/blood.2023023210. Online ahead of print. Blood. 2024. PMID: 39571145
Factors Associated With Increased Risk of Contamination in Bone Marrow Transplants.
Somasundaram E, Gill R, Hartford N, Collier K, McAfee SM, Dey BR, El-Jawahri A, DeFilipp Z, Frigault M, Leick M, Newcomb R, O'Donnell PV, Chen YB, Spitzer TR. Somasundaram E, et al. Among authors: leick m. Transplant Cell Ther. 2024 Nov 13:S2666-6367(24)00748-6. doi: 10.1016/j.jtct.2024.11.002. Online ahead of print. Transplant Cell Ther. 2024. PMID: 39542361
Comparative analysis of Bcl-2 family protein overexpression in CAR T cells alone and in combination with BH3 mimetics.
Korell F, Olson ML, Salas-Benito D, Leick MB, Larson RC, Bouffard A, Silva H, Gasparetto A, Berger TR, Kann MC, Mergen M, Kienka T, Wehrli M, Haradhvala NJ, Bailey SR, Letai A, Maus MV. Korell F, et al. Among authors: leick mb. Sci Transl Med. 2024 Jun 5;16(750):eadk7640. doi: 10.1126/scitranslmed.adk7640. Epub 2024 Jun 5. Sci Transl Med. 2024. PMID: 38838132
Phase 1 study of CAR-37 T cells in patients with relapsed or refractory CD37+ lymphoid malignancies.
Frigault MJ, Graham CE, Berger TR, Ritchey J, Horick NK, El-Jawahri A, Scarfò I, Schmidts A, Haradhvala NJ, Wehrli M, Lee WH, Parker AL, Wiggin HR, Bouffard A, Dey A, Leick MB, Katsis K, Elder EL, Dolaher MA, Cook DT, Chekmasova AA, Huang L, Nikiforow S, Daley H, Ritz J, Armant M, Preffer F, DiPersio JF, Nardi V, Chen YB, Gallagher KME, Maus MV. Frigault MJ, et al. Among authors: leick mb. Blood. 2024 Sep 12;144(11):1153-1167. doi: 10.1182/blood.2024024104. Blood. 2024. PMID: 38781564 Clinical Trial.
Stealth transgenes enable CAR-T cells to evade host immune responses.
Grauwet K, Berger T, Kann MC, Silva H, Larson R, Leick MB, Bailey SR, Bouffard AA, Millar D, Gallagher K, Turtle CJ, Frigault MJ, Maus MV. Grauwet K, et al. Among authors: leick mb. J Immunother Cancer. 2024 May 9;12(5):e008417. doi: 10.1136/jitc-2023-008417. J Immunother Cancer. 2024. PMID: 38724463 Free PMC article.
Intraventricular CARv3-TEAM-E T Cells in Recurrent Glioblastoma.
Choi BD, Gerstner ER, Frigault MJ, Leick MB, Mount CW, Balaj L, Nikiforow S, Carter BS, Curry WT, Gallagher K, Maus MV. Choi BD, et al. Among authors: leick mb. N Engl J Med. 2024 Apr 11;390(14):1290-1298. doi: 10.1056/NEJMoa2314390. Epub 2024 Mar 13. N Engl J Med. 2024. PMID: 38477966 Free PMC article.
60 results