Tang D - Search Results

1

A peptide-based positron emission tomography probe for in vivo detection of caspase activity in apoptotic cells.

Hight MR, Cheung YY, Nickels ML, Dawson ES, Zhao P, Saleh S, Buck JR, Tang D, Washington MK, Coffey RJ, Manning HC. Hight MR, et al. Among authors: tang d. Clin Cancer Res. 2014 Apr 15;20(8):2126-35. doi: 10.1158/1078-0432.CCR-13-2444. Epub 2014 Feb 26. Clin Cancer Res. 2014. PMID: 24573549 Free PMC article.

2

Synthesis and structure-activity relationships of 5,6,7-substituted pyrazolopyrimidines: discovery of a novel TSPO PET ligand for cancer imaging.

Tang D, McKinley ET, Hight MR, Uddin MI, Harp JM, Fu A, Nickels ML, Buck JR, Manning HC. Tang D, et al. J Med Chem. 2013 Apr 25;56(8):3429-33. doi: 10.1021/jm4001874. Epub 2013 Apr 3. J Med Chem. 2013. PMID: 23521048 Free PMC article.

3

Preclinical imaging evaluation of novel TSPO-PET ligand 2-(5,7-Diethyl-2-(4-(2-[(18)F]fluoroethoxy)phenyl)pyrazolo[1,5-a]pyrimidin-3-yl)-N,N-diethylacetamide ([ (18)F]VUIIS1008) in glioma.

Tang D, Nickels ML, Tantawy MN, Buck JR, Manning HC. Tang D, et al. Mol Imaging Biol. 2014 Dec;16(6):813-20. doi: 10.1007/s11307-014-0743-2. Mol Imaging Biol. 2014. PMID: 24845529 Free PMC article.

4

Evaluation of TSPO PET Ligands [¹⁸F]VUIIS1009A and [¹⁸F]VUIIS1009B: Tracers for Cancer Imaging.

Tang D, Li J, Buck JR, Tantawy MN, Xia Y, Harp JM, Nickels ML, Meiler J, Manning HC. Tang D, et al. Mol Imaging Biol. 2017 Aug;19(4):578-588. doi: 10.1007/s11307-016-1027-9. Mol Imaging Biol. 2017. PMID: 27853987 Free PMC article.

5

Microwave-assisted Organic Synthesis of a High-affinity Pyrazolo-pyrimidinyl TSPO Ligand.

Tang D, Buck JR, Hight MR, Manning HC. Tang D, et al. Tetrahedron Lett. 2010 Sep 1;51(35):4595-4598. doi: 10.1016/j.tetlet.2010.06.074. Tetrahedron Lett. 2010. PMID: 20689673 Free PMC article.

6

Quantitative, preclinical PET of translocator protein expression in glioma using 18F-N-fluoroacetyl-N-(2,5-dimethoxybenzyl)-2-phenoxyaniline.

Buck JR, McKinley ET, Hight MR, Fu A, Tang D, Smith RA, Tantawy MN, Peterson TE, Colvin D, Ansari MS, Baldwin RM, Zhao P, Guleryuz S, Manning HC. Buck JR, et al. Among authors: tang d. J Nucl Med. 2011 Jan;52(1):107-14. doi: 10.2967/jnumed.110.081703. Epub 2010 Dec 13. J Nucl Med. 2011. PMID: 21149488 Free PMC article.

7

Quantitative preclinical imaging of TSPO expression in glioma using N,N-diethyl-2-(2-(4-(2-18F-fluoroethoxy)phenyl)-5,7-dimethylpyrazolo[1,5-a]pyrimidin-3-yl)acetamide.

Tang D, Hight MR, McKinley ET, Fu A, Buck JR, Smith RA, Tantawy MN, Peterson TE, Colvin DC, Ansari MS, Nickels M, Manning HC. Tang D, et al. J Nucl Med. 2012 Feb;53(2):287-94. doi: 10.2967/jnumed.111.095653. Epub 2012 Jan 17. J Nucl Med. 2012. PMID: 22251555 Free PMC article.

8

Microwave-assisted, one-pot reaction of 7-azaindoles and aldehydes: a facile route to novel di-7-azaindolylmethanes.

Uddin MI, Buck JR, Schulte ML, Tang D, Saleh SA, Cheung YY, Harp J, Manning HC. Uddin MI, et al. Among authors: tang d. Tetrahedron Lett. 2014 Jan 1;55(1):10.1016/j.tetlet.2013.10.143. doi: 10.1016/j.tetlet.2013.10.143. Tetrahedron Lett. 2014. PMID: 24396154 Free PMC article.

9

Facile synthesis of SSR180575 and discovery of 7-chloro-N,N,5-trimethyl-4-oxo-3(6-[(18)F]fluoropyridin-2-yl)-3,5-dihydro-4H-pyridazino[4,5-b]indole-1-acetamide, a potent pyridazinoindole ligand for PET imaging of TSPO in cancer.

Cheung YY, Nickels ML, Tang D, Buck JR, Manning HC. Cheung YY, et al. Among authors: tang d. Bioorg Med Chem Lett. 2014 Sep 15;24(18):4466-4471. doi: 10.1016/j.bmcl.2014.07.091. Epub 2014 Aug 8. Bioorg Med Chem Lett. 2014. PMID: 25172419 Free PMC article.

10

Preclinical Evaluation of a Novel TSPO PET Ligand 2-(7-Butyl-2-(4-(2-[¹⁸F]Fluoroethoxy)phenyl)-5-Methylpyrazolo[1,5-a]Pyrimidin-3-yl)-N,N-Diethylacetamide (¹⁸F-VUIIS1018A) to Image Glioma.

Tang D, Li J, Nickels ML, Huang G, Cohen AS, Manning HC. Tang D, et al. Mol Imaging Biol. 2019 Feb;21(1):113-121. doi: 10.1007/s11307-018-1198-7. Mol Imaging Biol. 2019. PMID: 29869061 Free PMC article.

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