Zhao Y - Search Results

1

Mesothelin-specific chimeric antigen receptor mRNA-engineered T cells induce anti-tumor activity in solid malignancies.

Beatty GL, Haas AR, Maus MV, Torigian DA, Soulen MC, Plesa G, Chew A, Zhao Y, Levine BL, Albelda SM, Kalos M, June CH. Beatty GL, et al. Among authors: zhao y. Cancer Immunol Res. 2014 Feb;2(2):112-20. doi: 10.1158/2326-6066.CIR-13-0170. Cancer Immunol Res. 2014. PMID: 24579088 Free PMC article. Clinical Trial.

2

Enhanced antitumor activity of murine-human hybrid T-cell receptor (TCR) in human lymphocytes is associated with improved pairing and TCR/CD3 stability.

Cohen CJ, Zhao Y, Zheng Z, Rosenberg SA, Morgan RA. Cohen CJ, et al. Among authors: zhao y. Cancer Res. 2006 Sep 1;66(17):8878-86. doi: 10.1158/0008-5472.CAN-06-1450. Cancer Res. 2006. PMID: 16951205 Free PMC article.

3

Extrathymic generation of tumor-specific T cells from genetically engineered human hematopoietic stem cells via Notch signaling.

Zhao Y, Parkhurst MR, Zheng Z, Cohen CJ, Riley JP, Gattinoni L, Restifo NP, Rosenberg SA, Morgan RA. Zhao Y, et al. Cancer Res. 2007 Mar 15;67(6):2425-9. doi: 10.1158/0008-5472.CAN-06-3977. Cancer Res. 2007. PMID: 17363559 Free PMC article.

4

Recognition of NY-ESO-1+ tumor cells by engineered lymphocytes is enhanced by improved vector design and epigenetic modulation of tumor antigen expression.

Wargo JA, Robbins PF, Li Y, Zhao Y, El-Gamil M, Caragacianu D, Zheng Z, Hong JA, Downey S, Schrump DS, Rosenberg SA, Morgan RA. Wargo JA, et al. Among authors: zhao y. Cancer Immunol Immunother. 2009 Mar;58(3):383-94. doi: 10.1007/s00262-008-0562-x. Epub 2008 Aug 2. Cancer Immunol Immunother. 2009. PMID: 18677478 Free PMC article.

5

A herceptin-based chimeric antigen receptor with modified signaling domains leads to enhanced survival of transduced T lymphocytes and antitumor activity.

Zhao Y, Wang QJ, Yang S, Kochenderfer JN, Zheng Z, Zhong X, Sadelain M, Eshhar Z, Rosenberg SA, Morgan RA. Zhao Y, et al. J Immunol. 2009 Nov 1;183(9):5563-74. doi: 10.4049/jimmunol.0900447. J Immunol. 2009. PMID: 19843940 Free PMC article.

6

A high molecular weight melanoma-associated antigen-specific chimeric antigen receptor redirects lymphocytes to target human melanomas.

Burns WR, Zhao Y, Frankel TL, Hinrichs CS, Zheng Z, Xu H, Feldman SA, Ferrone S, Rosenberg SA, Morgan RA. Burns WR, et al. Among authors: zhao y. Cancer Res. 2010 Apr 15;70(8):3027-33. doi: 10.1158/0008-5472.CAN-09-2824. Cancer Res. 2010. PMID: 20395199 Free PMC article.

7

Multiple injections of electroporated autologous T cells expressing a chimeric antigen receptor mediate regression of human disseminated tumor.

Zhao Y, Moon E, Carpenito C, Paulos CM, Liu X, Brennan AL, Chew A, Carroll RG, Scholler J, Levine BL, Albelda SM, June CH. Zhao Y, et al. Cancer Res. 2010 Nov 15;70(22):9053-61. doi: 10.1158/0008-5472.CAN-10-2880. Epub 2010 Oct 5. Cancer Res. 2010. PMID: 20926399 Free PMC article.

8

Treatment of advanced leukemia in mice with mRNA engineered T cells.

Barrett DM, Zhao Y, Liu X, Jiang S, Carpenito C, Kalos M, Carroll RG, June CH, Grupp SA. Barrett DM, et al. Among authors: zhao y. Hum Gene Ther. 2011 Dec;22(12):1575-86. doi: 10.1089/hum.2011.070. Epub 2011 Sep 23. Hum Gene Ther. 2011. PMID: 21838572 Free PMC article.

9

TCR affinity and specificity requirements for human regulatory T-cell function.

Plesa G, Zheng L, Medvec A, Wilson CB, Robles-Oteiza C, Liddy N, Bennett AD, Gavarret J, Vuidepot A, Zhao Y, Blazar BR, Jakobsen BK, Riley JL. Plesa G, et al. Among authors: zhao y. Blood. 2012 Apr 12;119(15):3420-30. doi: 10.1182/blood-2011-09-377051. Epub 2012 Feb 7. Blood. 2012. PMID: 22318202 Free PMC article.

10

Enhanced function of redirected human T cells expressing linker for activation of T cells that is resistant to ubiquitylation.

Kunii N, Zhao Y, Jiang S, Liu X, Scholler J, Balagopalan L, Samelson LE, Milone MC, June CH. Kunii N, et al. Among authors: zhao y. Hum Gene Ther. 2013 Jan;24(1):27-37. doi: 10.1089/hum.2012.130. Epub 2012 Nov 6. Hum Gene Ther. 2013. PMID: 22998346 Free PMC article.

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