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Escherichia coli isolates from inflammatory bowel diseases patients survive in macrophages and activate NLRP3 inflammasome.
De la Fuente M, Franchi L, Araya D, Díaz-Jiménez D, Olivares M, Álvarez-Lobos M, Golenbock D, González MJ, López-Kostner F, Quera R, Núñez G, Vidal R, Hermoso MA. De la Fuente M, et al. Among authors: golenbock d. Int J Med Microbiol. 2014 May;304(3-4):384-92. doi: 10.1016/j.ijmm.2014.01.002. Epub 2014 Feb 6. Int J Med Microbiol. 2014. PMID: 24581881 Free PMC article.
RNA and β-hemolysin of group B Streptococcus induce interleukin-1β (IL-1β) by activating NLRP3 inflammasomes in mouse macrophages.
Gupta R, Ghosh S, Monks B, DeOliveira RB, Tzeng TC, Kalantari P, Nandy A, Bhattacharjee B, Chan J, Ferreira F, Rathinam V, Sharma S, Lien E, Silverman N, Fitzgerald K, Firon A, Trieu-Cuot P, Henneke P, Golenbock DT. Gupta R, et al. J Biol Chem. 2014 May 16;289(20):13701-5. doi: 10.1074/jbc.C114.548982. Epub 2014 Apr 1. J Biol Chem. 2014. PMID: 24692555 Free PMC article.
NLRP3 inflammasome activation drives tau pathology.
Ising C, Venegas C, Zhang S, Scheiblich H, Schmidt SV, Vieira-Saecker A, Schwartz S, Albasset S, McManus RM, Tejera D, Griep A, Santarelli F, Brosseron F, Opitz S, Stunden J, Merten M, Kayed R, Golenbock DT, Blum D, Latz E, Buée L, Heneka MT. Ising C, et al. Among authors: golenbock dt. Nature. 2019 Nov;575(7784):669-673. doi: 10.1038/s41586-019-1769-z. Epub 2019 Nov 20. Nature. 2019. PMID: 31748742 Free PMC article.
Malaria-induced NLRP12/NLRP3-dependent caspase-1 activation mediates inflammation and hypersensitivity to bacterial superinfection.
Ataide MA, Andrade WA, Zamboni DS, Wang D, Souza Mdo C, Franklin BS, Elian S, Martins FS, Pereira D, Reed G, Fitzgerald KA, Golenbock DT, Gazzinelli RT. Ataide MA, et al. Among authors: golenbock dt. PLoS Pathog. 2014 Jan;10(1):e1003885. doi: 10.1371/journal.ppat.1003885. Epub 2014 Jan 16. PLoS Pathog. 2014. PMID: 24453977 Free PMC article. Clinical Trial.
Hemolysis-induced lethality involves inflammasome activation by heme.
Dutra FF, Alves LS, Rodrigues D, Fernandez PL, de Oliveira RB, Golenbock DT, Zamboni DS, Bozza MT. Dutra FF, et al. Among authors: golenbock dt. Proc Natl Acad Sci U S A. 2014 Sep 30;111(39):E4110-8. doi: 10.1073/pnas.1405023111. Epub 2014 Sep 15. Proc Natl Acad Sci U S A. 2014. PMID: 25225402 Free PMC article.
300 results