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502 results

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Page 1
Protective immunity and defects in the neonatal and elderly immune response to sepsis.
Gentile LF, Nacionales DC, Lopez MC, Vanzant E, Cuenca A, Cuenca AG, Ungaro R, Szpila BE, Larson S, Joseph A, Moore FA, Leeuwenburgh C, Baker HV, Moldawer LL, Efron PA. Gentile LF, et al. Among authors: moore fa. J Immunol. 2014 Apr 1;192(7):3156-65. doi: 10.4049/jimmunol.1301726. Epub 2014 Mar 3. J Immunol. 2014. PMID: 24591376 Free PMC article.
Identification and description of a novel murine model for polytrauma and shock.
Gentile LF, Nacionales DC, Cuenca AG, Armbruster M, Ungaro RF, Abouhamze AS, Lopez C, Baker HV, Moore FA, Ang DN, Efron PA. Gentile LF, et al. Among authors: moore fa. Crit Care Med. 2013 Apr;41(4):1075-85. doi: 10.1097/CCM.0b013e318275d1f9. Crit Care Med. 2013. PMID: 23399937 Free PMC article.
Aged mice are unable to mount an effective myeloid response to sepsis.
Nacionales DC, Gentile LF, Vanzant E, Lopez MC, Cuenca A, Cuenca AG, Ungaro R, Li Y, Baslanti TO, Bihorac A, Moore FA, Baker HV, Leeuwenburgh C, Moldawer LL, Efron PA. Nacionales DC, et al. Among authors: moore fa. J Immunol. 2014 Jan 15;192(2):612-22. doi: 10.4049/jimmunol.1302109. Epub 2013 Dec 13. J Immunol. 2014. PMID: 24337739 Free PMC article.
Persistent inflammation, immunosuppression, and catabolism syndrome after severe blunt trauma.
Vanzant EL, Lopez CM, Ozrazgat-Baslanti T, Ungaro R, Davis R, Cuenca AG, Gentile LF, Nacionales DC, Cuenca AL, Bihorac A, Leeuwenburgh C, Lanz J, Baker HV, McKinley B, Moldawer LL, Moore FA, Efron PA. Vanzant EL, et al. Among authors: moore fa. J Trauma Acute Care Surg. 2014 Jan;76(1):21-9; discussion 29-30. doi: 10.1097/TA.0b013e3182ab1ab5. J Trauma Acute Care Surg. 2014. PMID: 24368353 Free PMC article.
A better understanding of why murine models of trauma do not recapitulate the human syndrome.
Gentile LF, Nacionales DC, Lopez MC, Vanzant E, Cuenca A, Cuenca AG, Ungaro R, Baslanti TO, McKinley BA, Bihorac A, Cuschieri J, Maier RV, Moore FA, Leeuwenburgh C, Baker HV, Moldawer LL, Efron PA. Gentile LF, et al. Among authors: moore fa. Crit Care Med. 2014 Jun;42(6):1406-13. doi: 10.1097/CCM.0000000000000222. Crit Care Med. 2014. PMID: 24413577 Free PMC article.
Host responses to sepsis vary in different low-lethality murine models.
Gentile LF, Nacionales DC, Lopez MC, Vanzant E, Cuenca A, Szpila BE, Cuenca AG, Joseph A, Moore FA, Leeuwenburgh C, Baker HV, Moldawer LL, Efron PA. Gentile LF, et al. Among authors: moore fa. PLoS One. 2014 May 1;9(5):e94404. doi: 10.1371/journal.pone.0094404. eCollection 2014. PLoS One. 2014. PMID: 24788351 Free PMC article.
A Detailed Characterization of the Dysfunctional Immunity and Abnormal Myelopoiesis Induced by Severe Shock and Trauma in the Aged.
Nacionales DC, Szpila B, Ungaro R, Lopez MC, Zhang J, Gentile LF, Cuenca AL, Vanzant E, Mathias B, Jyot J, Westerveld D, Bihorac A, Joseph A, Mohr A, Duckworth LV, Moore FA, Baker HV, Leeuwenburgh C, Moldawer LL, Brakenridge S, Efron PA. Nacionales DC, et al. Among authors: moore fa. J Immunol. 2015 Sep 1;195(5):2396-407. doi: 10.4049/jimmunol.1500984. Epub 2015 Aug 5. J Immunol. 2015. PMID: 26246141 Free PMC article.
Patterns of gene expression among murine models of hemorrhagic shock/trauma and sepsis.
Mira JC, Szpila BE, Nacionales DC, Lopez MC, Gentile LF, Mathias BJ, Vanzant EL, Ungaro R, Holden D, Rosenthal MD, Rincon J, Verdugo PT, Larson SD, Moore FA, Brakenridge SC, Mohr AM, Baker HV, Moldawer LL, Efron PA. Mira JC, et al. Among authors: moore fa. Physiol Genomics. 2016 Feb;48(2):135-44. doi: 10.1152/physiolgenomics.00072.2015. Epub 2015 Nov 17. Physiol Genomics. 2016. PMID: 26578697 Free PMC article.
Old Mice Demonstrate Organ Dysfunction as well as Prolonged Inflammation, Immunosuppression, and Weight Loss in a Modified Surgical Sepsis Model.
Stortz JA, Hollen MK, Nacionales DC, Horiguchi H, Ungaro R, Dirain ML, Wang Z, Wu Q, Wu KK, Kumar A, Foster TC, Stewart BD, Ross JA, Segal M, Bihorac A, Brakenridge S, Moore FA, Wohlgemuth SE, Leeuwenburgh C, Mohr AM, Moldawer LL, Efron PA. Stortz JA, et al. Among authors: moore fa. Crit Care Med. 2019 Nov;47(11):e919-e929. doi: 10.1097/CCM.0000000000003926. Crit Care Med. 2019. PMID: 31389840 Free PMC article.
Transcriptomic responses from improved murine sepsis models can better mimic human surgical sepsis.
Efron PA, Darden DB, Wang Z, Nacionales DC, Lopez MC, Hawkins RB, Cox MC, Rincon JC, Ungaro R, Dirain ML, Ghita GL, Chen T, Billiar TR, Delano MJ, Leeuwenburgh C, Bihorac A, Brakenridge SC, Moore FA, Mohr AM, Tompkins RG, Brumback BA, Baker HV, Upchurch GR, Moldawer LL. Efron PA, et al. Among authors: moore fa. FASEB J. 2021 Feb;35(2):e21156. doi: 10.1096/fj.202002150R. Epub 2020 Nov 2. FASEB J. 2021. PMID: 33140449 Free PMC article.
502 results