Jackson JG - Search Results

1

Therapeutic efficacy of p53 restoration in Mdm2-overexpressing tumors.

Li Q, Zhang Y, El-Naggar AK, Xiong S, Yang P, Jackson JG, Chau G, Lozano G. Li Q, et al. Among authors: jackson jg. Mol Cancer Res. 2014 Jun;12(6):901-11. doi: 10.1158/1541-7786.MCR-14-0089. Epub 2014 Mar 5. Mol Cancer Res. 2014. PMID: 24598047 Free PMC article.

2

A high-frequency regulatory polymorphism in the p53 pathway accelerates tumor development.

Post SM, Quintás-Cardama A, Pant V, Iwakuma T, Hamir A, Jackson JG, Maccio DR, Bond GL, Johnson DG, Levine AJ, Lozano G. Post SM, et al. Among authors: jackson jg. Cancer Cell. 2010 Sep 14;18(3):220-30. doi: 10.1016/j.ccr.2010.07.010. Cancer Cell. 2010. PMID: 20832750 Free PMC article.

3

Regulation of tissue- and stimulus-specific cell fate decisions by p53 in vivo.

Jackson JG, Post SM, Lozano G. Jackson JG, et al. J Pathol. 2011 Jan;223(2):127-36. doi: 10.1002/path.2783. Epub 2010 Oct 18. J Pathol. 2011. PMID: 20957626 Review.

4

Mdm2 is required for survival of hematopoietic stem cells/progenitors via dampening of ROS-induced p53 activity.

Abbas HA, Maccio DR, Coskun S, Jackson JG, Hazen AL, Sills TM, You MJ, Hirschi KK, Lozano G. Abbas HA, et al. Among authors: jackson jg. Cell Stem Cell. 2010 Nov 5;7(5):606-17. doi: 10.1016/j.stem.2010.09.013. Cell Stem Cell. 2010. PMID: 21040902 Free PMC article.

5

Restoring expression of wild-type p53 suppresses tumor growth but does not cause tumor regression in mice with a p53 missense mutation.

Wang Y, Suh YA, Fuller MY, Jackson JG, Xiong S, Terzian T, Quintás-Cardama A, Bankson JA, El-Naggar AK, Lozano G. Wang Y, et al. Among authors: jackson jg. J Clin Invest. 2011 Mar;121(3):893-904. doi: 10.1172/JCI44504. J Clin Invest. 2011. PMID: 21285512 Free PMC article.

6

Multiple stress signals activate mutant p53 in vivo.

Suh YA, Post SM, Elizondo-Fraire AC, Maccio DR, Jackson JG, El-Naggar AK, Van Pelt C, Terzian T, Lozano G. Suh YA, et al. Among authors: jackson jg. Cancer Res. 2011 Dec 1;71(23):7168-75. doi: 10.1158/0008-5472.CAN-11-0459. Epub 2011 Oct 7. Cancer Res. 2011. PMID: 21983037 Free PMC article.

7

Mutant p53 disrupts role of ShcA protein in balancing Smad protein-dependent and -independent signaling activity of transforming growth factor-β (TGF-β).

Lin S, Yu L, Yang J, Liu Z, Karia B, Bishop AJR, Jackson J, Lozano G, Copland JA, Mu X, Sun B, Sun LZ. Lin S, et al. J Biol Chem. 2011 Dec 23;286(51):44023-44034. doi: 10.1074/jbc.M111.265397. Epub 2011 Oct 28. J Biol Chem. 2011. PMID: 22039050 Free PMC article.

8

p53-mediated senescence impairs the apoptotic response to chemotherapy and clinical outcome in breast cancer.

Jackson JG, Pant V, Li Q, Chang LL, Quintás-Cardama A, Garza D, Tavana O, Yang P, Manshouri T, Li Y, El-Naggar AK, Lozano G. Jackson JG, et al. Cancer Cell. 2012 Jun 12;21(6):793-806. doi: 10.1016/j.ccr.2012.04.027. Cancer Cell. 2012. PMID: 22698404 Free PMC article.

9

Che-ating death: CHE1/AATF protects from p53-mediated apoptosis.

Jackson JG, Lozano G. Jackson JG, et al. EMBO J. 2012 Oct 17;31(20):3951-3. doi: 10.1038/emboj.2012.258. Epub 2012 Sep 7. EMBO J. 2012. PMID: 22960635 Free PMC article.

10

The mutant p53 mouse as a pre-clinical model.

Jackson JG, Lozano G. Jackson JG, et al. Oncogene. 2013 Sep 12;32(37):4325-30. doi: 10.1038/onc.2012.610. Epub 2013 Jan 14. Oncogene. 2013. PMID: 23318424 Review.

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