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Extended structure-activity relationship and pharmacokinetic investigation of (4-quinolinoyl)glycyl-2-cyanopyrrolidine inhibitors of fibroblast activation protein (FAP).
Jansen K, Heirbaut L, Verkerk R, Cheng JD, Joossens J, Cos P, Maes L, Lambeir AM, De Meester I, Augustyns K, Van der Veken P. Jansen K, et al. Among authors: van der veken p. J Med Chem. 2014 Apr 10;57(7):3053-74. doi: 10.1021/jm500031w. Epub 2014 Mar 24. J Med Chem. 2014. PMID: 24617858
Development of potent and selective dipeptidyl peptidase II inhibitors.
Senten K, Van der Veken P, Bal G, De Meester I, Lambeir AM, Scharpé S, Bauvois B, Haemers A, Augustyns K. Senten K, et al. Among authors: van der veken p. Bioorg Med Chem Lett. 2002 Oct 21;12(20):2825-8. doi: 10.1016/s0960-894x(02)00603-0. Bioorg Med Chem Lett. 2002. PMID: 12270155
Kinetic investigation of human dipeptidyl peptidase II (DPPII)-mediated hydrolysis of dipeptide derivatives and its identification as quiescent cell proline dipeptidase (QPP)/dipeptidyl peptidase 7 (DPP7).
Maes MB, Lambeir AM, Gilany K, Senten K, Van der Veken P, Leiting B, Augustyns K, Scharpé S, De Meester I. Maes MB, et al. Among authors: van der veken p. Biochem J. 2005 Mar 1;386(Pt 2):315-24. doi: 10.1042/BJ20041156. Biochem J. 2005. PMID: 15487984 Free PMC article.
162 results