Piazza G - Search Results

1

Autocrine fibroblast growth factor 18 signaling mediates Wnt-dependent stimulation of CD44-positive human colorectal adenoma cells.

Koneczny I, Schulenburg A, Hudec X, Knöfler M, Holzmann K, Piazza G, Reynolds R, Valent P, Marian B. Koneczny I, et al. Among authors: piazza g. Mol Carcinog. 2015 Sep;54(9):789-799. doi: 10.1002/mc.22146. Epub 2014 Mar 12. Mol Carcinog. 2015. PMID: 24619956 Free PMC article.

2

Suppression of Wnt/beta-catenin signaling inhibits prostate cancer cell proliferation.

Lu W, Tinsley HN, Keeton A, Qu Z, Piazza GA, Li Y. Lu W, et al. Eur J Pharmacol. 2009 Jan 5;602(1):8-14. doi: 10.1016/j.ejphar.2008.10.053. Epub 2008 Nov 9. Eur J Pharmacol. 2009. PMID: 19026633 Free PMC article.

3

A novel sulindac derivative that does not inhibit cyclooxygenases but potently inhibits colon tumor cell growth and induces apoptosis with antitumor activity.

Piazza GA, Keeton AB, Tinsley HN, Gary BD, Whitt JD, Mathew B, Thaiparambil J, Coward L, Gorman G, Li Y, Sani B, Hobrath JV, Maxuitenko YY, Reynolds RC. Piazza GA, et al. Cancer Prev Res (Phila). 2009 Jun;2(6):572-80. doi: 10.1158/1940-6207.CAPR-09-0001. Epub 2009 May 26. Cancer Prev Res (Phila). 2009. PMID: 19470791 Free PMC article.

4

Sulindac sulfide selectively inhibits growth and induces apoptosis of human breast tumor cells by phosphodiesterase 5 inhibition, elevation of cyclic GMP, and activation of protein kinase G.

Tinsley HN, Gary BD, Keeton AB, Zhang W, Abadi AH, Reynolds RC, Piazza GA. Tinsley HN, et al. Mol Cancer Ther. 2009 Dec;8(12):3331-40. doi: 10.1158/1535-7163.MCT-09-0758. Mol Cancer Ther. 2009. PMID: 19996273 Free PMC article.

5

A novel sulindac derivative lacking cyclooxygenase-inhibitory activities suppresses carcinogenesis in the transgenic adenocarcinoma of mouse prostate model.

Zhang Y, Zhang J, Wang L, Quealy E, Gary BD, Reynolds RC, Piazza GA, Lü J. Zhang Y, et al. Cancer Prev Res (Phila). 2010 Jul;3(7):885-95. doi: 10.1158/1940-6207.CAPR-09-0273. Epub 2010 Jun 29. Cancer Prev Res (Phila). 2010. PMID: 20587701 Free PMC article.

6

Inhibition of PDE5 by sulindac sulfide selectively induces apoptosis and attenuates oncogenic Wnt/β-catenin-mediated transcription in human breast tumor cells.

Tinsley HN, Gary BD, Keeton AB, Lu W, Li Y, Piazza GA. Tinsley HN, et al. Cancer Prev Res (Phila). 2011 Aug;4(8):1275-84. doi: 10.1158/1940-6207.CAPR-11-0095. Epub 2011 Apr 19. Cancer Prev Res (Phila). 2011. PMID: 21505183 Free PMC article.

7

A novel sulindac derivative inhibits lung adenocarcinoma cell growth through suppression of Akt/mTOR signaling and induction of autophagy.

Gurpinar E, Grizzle WE, Shacka JJ, Mader BJ, Li N, Piazza NA, Russo S, Keeton AB, Piazza GA. Gurpinar E, et al. Mol Cancer Ther. 2013 May;12(5):663-74. doi: 10.1158/1535-7163.MCT-12-0785. Epub 2013 Feb 26. Mol Cancer Ther. 2013. PMID: 23443799 Free PMC article.

8

Sulindac selectively inhibits colon tumor cell growth by activating the cGMP/PKG pathway to suppress Wnt/β-catenin signaling.

Li N, Xi Y, Tinsley HN, Gurpinar E, Gary BD, Zhu B, Li Y, Chen X, Keeton AB, Abadi AH, Moyer MP, Grizzle WE, Chang WC, Clapper ML, Piazza GA. Li N, et al. Mol Cancer Ther. 2013 Sep;12(9):1848-59. doi: 10.1158/1535-7163.MCT-13-0048. Epub 2013 Jun 26. Mol Cancer Ther. 2013. PMID: 23804703 Free PMC article.

9

β-catenin nuclear translocation in colorectal cancer cells is suppressed by PDE10A inhibition, cGMP elevation, and activation of PKG.

Lee K, Lindsey AS, Li N, Gary B, Andrews J, Keeton AB, Piazza GA. Lee K, et al. Oncotarget. 2016 Feb 2;7(5):5353-65. doi: 10.18632/oncotarget.6705. Oncotarget. 2016. PMID: 26713600 Free PMC article.

10

NSAIDs: Old Drugs Reveal New Anticancer Targets.

Piazza GA, Keeton AB, Tinsley HN, Whitt JD, Gary BD, Mathew B, Singh R, Grizzle WE, Reynolds RC. Piazza GA, et al. Pharmaceuticals (Basel). 2010 May 25;3(5):1652-1667. doi: 10.3390/ph3051652. Pharmaceuticals (Basel). 2010. PMID: 27713322 Free PMC article. Review.

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