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RUNX2 correlates with subtype-specific breast cancer in a human tissue microarray, and ectopic expression of Runx2 perturbs differentiation in the mouse mammary gland.
McDonald L, Ferrari N, Terry A, Bell M, Mohammed ZM, Orange C, Jenkins A, Muller WJ, Gusterson BA, Neil JC, Edwards J, Morris JS, Cameron ER, Blyth K. McDonald L, et al. Among authors: orange c. Dis Model Mech. 2014 May;7(5):525-34. doi: 10.1242/dmm.015040. Epub 2014 Mar 13. Dis Model Mech. 2014. PMID: 24626992 Free PMC article.
High expression of sphingosine 1-phosphate receptors, S1P1 and S1P3, sphingosine kinase 1, and extracellular signal-regulated kinase-1/2 is associated with development of tamoxifen resistance in estrogen receptor-positive breast cancer patients.
Watson C, Long JS, Orange C, Tannahill CL, Mallon E, McGlynn LM, Pyne S, Pyne NJ, Edwards J. Watson C, et al. Among authors: orange c. Am J Pathol. 2010 Nov;177(5):2205-15. doi: 10.2353/ajpath.2010.100220. Epub 2010 Oct 1. Am J Pathol. 2010. PMID: 20889557 Free PMC article.
The relationship between tumour necrosis, tumour proliferation, local and systemic inflammation, microvessel density and survival in patients undergoing potentially curative resection of oesophageal adenocarcinoma.
Dutta S, Going JJ, Crumley AB, Mohammed Z, Orange C, Edwards J, Fullarton GM, Horgan PG, McMillan DC. Dutta S, et al. Among authors: orange c. Br J Cancer. 2012 Feb 14;106(4):702-10. doi: 10.1038/bjc.2011.610. Epub 2012 Jan 12. Br J Cancer. 2012. PMID: 22240784 Free PMC article.
Identification of novel functional and spatial associations between sphingosine kinase 1, sphingosine 1-phosphate receptors and other signaling proteins that affect prognostic outcome in estrogen receptor-positive breast cancer.
Ohotski J, Edwards J, Elsberger B, Watson C, Orange C, Mallon E, Pyne S, Pyne NJ. Ohotski J, et al. Among authors: orange c. Int J Cancer. 2013 Feb 1;132(3):605-16. doi: 10.1002/ijc.27692. Epub 2012 Jul 11. Int J Cancer. 2013. PMID: 22733311
100 results