Cihlar T - Search Results

1

Contribution of the organic anion transporter OAT2 to the renal active tubular secretion of creatinine and mechanism for serum creatinine elevations caused by cobicistat.

Lepist EI, Zhang X, Hao J, Huang J, Kosaka A, Birkus G, Murray BP, Bannister R, Cihlar T, Huang Y, Ray AS. Lepist EI, et al. Among authors: cihlar t. Kidney Int. 2014 Aug;86(2):350-7. doi: 10.1038/ki.2014.66. Epub 2014 Mar 19. Kidney Int. 2014. PMID: 24646860 Free PMC article.

2

Cytotoxicity of antiviral nucleotides adefovir and cidofovir is induced by the expression of human renal organic anion transporter 1.

Ho ES, Lin DC, Mendel DB, Cihlar T. Ho ES, et al. Among authors: cihlar t. J Am Soc Nephrol. 2000 Mar;11(3):383-393. doi: 10.1681/ASN.V113383. J Am Soc Nephrol. 2000. PMID: 10703662

3

Fluorescence-based assay for the interaction of small molecules with the human renal organic anion transporter 1.

Cihlar T, Ho ES. Cihlar T, et al. Anal Biochem. 2000 Jul 15;283(1):49-55. doi: 10.1006/abio.2000.4633. Anal Biochem. 2000. PMID: 10929807

4

Nonsteroidal anti-inflammatory drugs efficiently reduce the transport and cytotoxicity of adefovir mediated by the human renal organic anion transporter 1.

Mulato AS, Ho ES, Cihlar T. Mulato AS, et al. Among authors: cihlar t. J Pharmacol Exp Ther. 2000 Oct;295(1):10-5. J Pharmacol Exp Ther. 2000. PMID: 10991954

5

Assessment of mitochondrial toxicity in human cells treated with tenofovir: comparison with other nucleoside reverse transcriptase inhibitors.

Birkus G, Hitchcock MJ, Cihlar T. Birkus G, et al. Among authors: cihlar t. Antimicrob Agents Chemother. 2002 Mar;46(3):716-23. doi: 10.1128/AAC.46.3.716-723.2002. Antimicrob Agents Chemother. 2002. PMID: 11850253 Free PMC article.

6

Tenofovir exhibits low cytotoxicity in various human cell types: comparison with other nucleoside reverse transcriptase inhibitors.

Cihlar T, Birkus G, Greenwalt DE, Hitchcock MJ. Cihlar T, et al. Antiviral Res. 2002 Apr;54(1):37-45. doi: 10.1016/s0166-3542(01)00210-8. Antiviral Res. 2002. PMID: 11888656

7

Comparative effects of adefovir and selected nucleoside inhibitors of hepatitis B virus DNA polymerase on mitochondrial DNA in liver and skeletal muscle cells.

Birkus G, Gibbs CS, Cihlar T. Birkus G, et al. Among authors: cihlar t. J Viral Hepat. 2003 Jan;10(1):50-4. doi: 10.1046/j.1365-2893.2003.00399.x. J Viral Hepat. 2003. PMID: 12558912

8

Mechanism of active renal tubular efflux of tenofovir.

Ray AS, Cihlar T, Robinson KL, Tong L, Vela JE, Fuller MD, Wieman LM, Eisenberg EJ, Rhodes GR. Ray AS, et al. Among authors: cihlar t. Antimicrob Agents Chemother. 2006 Oct;50(10):3297-304. doi: 10.1128/AAC.00251-06. Antimicrob Agents Chemother. 2006. PMID: 17005808 Free PMC article.

9

Cathepsin A is the major hydrolase catalyzing the intracellular hydrolysis of the antiretroviral nucleotide phosphonoamidate prodrugs GS-7340 and GS-9131.

Birkus G, Wang R, Liu X, Kutty N, MacArthur H, Cihlar T, Gibbs C, Swaminathan S, Lee W, McDermott M. Birkus G, et al. Among authors: cihlar t. Antimicrob Agents Chemother. 2007 Feb;51(2):543-50. doi: 10.1128/AAC.00968-06. Epub 2006 Dec 4. Antimicrob Agents Chemother. 2007. PMID: 17145787 Free PMC article.

10

Unlikely association of multidrug-resistance protein 2 single-nucleotide polymorphisms with tenofovir-induced renal adverse events.

Ray AS, Cihlar T. Ray AS, et al. Among authors: cihlar t. J Infect Dis. 2007 May 1;195(9):1389-90; author reply 1390-1. doi: 10.1086/513282. J Infect Dis. 2007. PMID: 17397012 No abstract available.

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