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Increased susceptibility to hyperoxic lung injury and alveolar simplification in newborn rats by prenatal administration of benzo[a]pyrene.
Thakur VS, Liang YW, Lingappan K, Jiang W, Wang L, Barrios R, Zhou G, Guntupalli B, Shivanna B, Maturu P, Welty SE, Moorthy B, Couroucli XI. Thakur VS, et al. Among authors: wang l. Toxicol Lett. 2014 Oct 15;230(2):322-32. doi: 10.1016/j.toxlet.2014.03.006. Epub 2014 Mar 19. Toxicol Lett. 2014. PMID: 24657529 Free PMC article.
Disruption of the gene for CYP1A2, which is expressed primarily in liver, leads to differential regulation of hepatic and pulmonary mouse CYP1A1 expression and augmented human CYP1A1 transcriptional activation in response to 3-methylcholanthrene in vivo.
Jiang W, Wang L, Kondraganti SR, Fazili IS, Couroucli XI, Felix EA, Moorthy B. Jiang W, et al. Among authors: wang l. J Pharmacol Exp Ther. 2010 Nov;335(2):369-79. doi: 10.1124/jpet.110.171173. Epub 2010 Aug 23. J Pharmacol Exp Ther. 2010. PMID: 20732958 Free PMC article.
Augmented oxygen-mediated transcriptional activation of cytochrome P450 (CYP)1A expression and increased susceptibilities to hyperoxic lung injury in transgenic mice carrying the human CYP1A1 or mouse 1A2 promoter in vivo.
Jiang W, Couroucli XI, Wang L, Barrios R, Moorthy B. Jiang W, et al. Among authors: wang l. Biochem Biophys Res Commun. 2011 Apr 1;407(1):79-85. doi: 10.1016/j.bbrc.2011.02.113. Epub 2011 Mar 6. Biochem Biophys Res Commun. 2011. PMID: 21362406 Free PMC article.
Prenatal administration of the cytochrome P4501A inducer, Β-naphthoflavone (BNF), attenuates hyperoxic lung injury in newborn mice: implications for bronchopulmonary dysplasia (BPD) in premature infants.
Couroucli XI, Liang YH, Jiang W, Wang L, Barrios R, Yang P, Moorthy B. Couroucli XI, et al. Among authors: wang l. Toxicol Appl Pharmacol. 2011 Oct 15;256(2):83-94. doi: 10.1016/j.taap.2011.06.018. Epub 2011 Jun 26. Toxicol Appl Pharmacol. 2011. PMID: 21745492 Free PMC article.
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