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Nedd8-activating enzyme inhibitor MLN4924 provides synergy with mitomycin C through interactions with ATR, BRCA1/BRCA2, and chromatin dynamics pathways.
Garcia K, Blank JL, Bouck DC, Liu XJ, Sappal DS, Hather G, Cosmopoulos K, Thomas MP, Kuranda M, Pickard MD, Liu R, Bandi S, Smith PG, Lightcap ES. Garcia K, et al. Among authors: hather g. Mol Cancer Ther. 2014 Jun;13(6):1625-35. doi: 10.1158/1535-7163.MCT-13-0634. Epub 2014 Mar 26. Mol Cancer Ther. 2014. PMID: 24672057
KRAS Genotype Correlates with Proteasome Inhibitor Ixazomib Activity in Preclinical In Vivo Models of Colon and Non-Small Cell Lung Cancer: Potential Role of Tumor Metabolism.
Chattopadhyay N, Berger AJ, Koenig E, Bannerman B, Garnsey J, Bernard H, Hales P, Maldonado Lopez A, Yang Y, Donelan J, Jordan K, Tirrell S, Stringer B, Xia C, Hather G, Galvin K, Manfredi M, Rhodes N, Amidon B. Chattopadhyay N, et al. Among authors: hather g. PLoS One. 2015 Dec 28;10(12):e0144825. doi: 10.1371/journal.pone.0144825. eCollection 2015. PLoS One. 2015. PMID: 26709701 Free PMC article.
The United States of America and scientific research.
Hather GJ, Haynes W, Higdon R, Kolker N, Stewart EA, Arzberger P, Chain P, Field D, Franza BR, Lin B, Meyer F, Ozdemir V, Smith CV, van Belle G, Wooley J, Kolker E. Hather GJ, et al. PLoS One. 2010 Aug 16;5(8):e12203. doi: 10.1371/journal.pone.0012203. PLoS One. 2010. PMID: 20808949 Free PMC article.
Machine Learning in Drug Discovery and Development Part 1: A Primer.
Talevi A, Morales JF, Hather G, Podichetty JT, Kim S, Bloomingdale PC, Kim S, Burton J, Brown JD, Winterstein AG, Schmidt S, White JK, Conrado DJ. Talevi A, et al. Among authors: hather g. CPT Pharmacometrics Syst Pharmacol. 2020 Mar;9(3):129-142. doi: 10.1002/psp4.12491. Epub 2020 Mar 11. CPT Pharmacometrics Syst Pharmacol. 2020. PMID: 31905263 Free PMC article.
25 results