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Page 1
Lineage-specific function of Engrailed-2 in the progression of chronic myelogenous leukemia to T-cell blast crisis.
Abollo-Jiménez F, Campos-Sánchez E, Toboso-Navasa A, Vicente-Dueñas C, González-Herrero I, Alonso-Escudero E, González M, Segura V, Blanco O, Martínez-Climent JA, Sánchez-García I, Cobaleda C. Abollo-Jiménez F, et al. Cell Cycle. 2014;13(11):1717-26. doi: 10.4161/cc.28629. Epub 2014 Mar 25. Cell Cycle. 2014. PMID: 24675889 Free PMC article.
Epigenetic regulation of miRNA genes in acute leukemia.
Agirre X, Martínez-Climent JÁ, Odero MD, Prósper F. Agirre X, et al. Leukemia. 2012 Mar;26(3):395-403. doi: 10.1038/leu.2011.344. Epub 2011 Dec 6. Leukemia. 2012. PMID: 22143672 Review.
Preclinical activity of LBH589 alone or in combination with chemotherapy in a xenogeneic mouse model of human acute lymphoblastic leukemia.
Vilas-Zornoza A, Agirre X, Abizanda G, Moreno C, Segura V, De Martino Rodriguez A, José-Eneriz ES, Miranda E, Martín-Subero JI, Garate L, Blanco-Prieto MJ, García de Jalón JA, Rio P, Rifón J, Cigudosa JC, Martinez-Climent JA, Román-Gómez J, Calasanz MJ, Ribera JM, Prósper F. Vilas-Zornoza A, et al. Leukemia. 2012 Jul;26(7):1517-26. doi: 10.1038/leu.2012.31. Epub 2012 Feb 6. Leukemia. 2012. PMID: 22307227 Free article.
Identification of LMO2 transcriptome and interactome in diffuse large B-cell lymphoma.
Cubedo E, Gentles AJ, Huang C, Natkunam Y, Bhatt S, Lu X, Jiang X, Romero-Camarero I, Freud A, Zhao S, Bacchi CE, Martínez-Climent JA, Sánchez-García I, Melnick A, Lossos IS. Cubedo E, et al. Blood. 2012 Jun 7;119(23):5478-91. doi: 10.1182/blood-2012-01-403154. Epub 2012 Apr 19. Blood. 2012. PMID: 22517897 Free PMC article.
Expression of MALT1 oncogene in hematopoietic stem/progenitor cells recapitulates the pathogenesis of human lymphoma in mice.
Vicente-Dueñas C, Fontán L, Gonzalez-Herrero I, Romero-Camarero I, Segura V, Aznar MA, Alonso-Escudero E, Campos-Sanchez E, Ruiz-Roca L, Barajas-Diego M, Sagardoy A, Martinez-Ferrandis JI, Abollo-Jimenez F, Bertolo C, Peñuelas I, Garcia-Criado FJ, García-Cenador MB, Tousseyn T, Agirre X, Prosper F, Garcia-Bragado F, McPhail ED, Lossos IS, Du MQ, Flores T, Hernandez-Rivas JM, Gonzalez M, Salar A, Bellosillo B, Conde E, Siebert R, Sagaert X, Cobaleda C, Sanchez-Garcia I, Martinez-Climent JA. Vicente-Dueñas C, et al. Proc Natl Acad Sci U S A. 2012 Jun 26;109(26):10534-9. doi: 10.1073/pnas.1204127109. Epub 2012 Jun 11. Proc Natl Acad Sci U S A. 2012. PMID: 22689981 Free PMC article.
MALT lymphoma meets stem cells.
Vicente-Dueñas C, Cobaleda C, Martínez-Climent JÁ, Sánchez-García I. Vicente-Dueñas C, et al. Cell Cycle. 2012 Aug 15;11(16):2961-2. doi: 10.4161/cc.21264. Epub 2012 Jul 24. Cell Cycle. 2012. PMID: 22825253 Free PMC article.
Germinal centre protein HGAL promotes lymphoid hyperplasia and amyloidosis via BCR-mediated Syk activation.
Romero-Camarero I, Jiang X, Natkunam Y, Lu X, Vicente-Dueñas C, Gonzalez-Herrero I, Flores T, Garcia JL, McNamara G, Kunder C, Zhao S, Segura V, Fontan L, Martínez-Climent JA, García-Criado FJ, Theis JD, Dogan A, Campos-Sánchez E, Green MR, Alizadeh AA, Cobaleda C, Sánchez-García I, Lossos IS. Romero-Camarero I, et al. Nat Commun. 2013;4:1338. doi: 10.1038/ncomms2334. Nat Commun. 2013. PMID: 23299888 Free PMC article.
Transient expression of Bcl6 is sufficient for oncogenic function and induction of mature B-cell lymphoma.
Green MR, Vicente-Dueñas C, Romero-Camarero I, Long Liu C, Dai B, González-Herrero I, García-Ramírez I, Alonso-Escudero E, Iqbal J, Chan WC, Campos-Sanchez E, Orfao A, Pintado B, Flores T, Blanco O, Jiménez R, Martínez-Climent JA, Criado FJ, Cenador MB, Zhao S, Natkunam Y, Lossos IS, Majeti R, Melnick A, Cobaleda C, Alizadeh AA, Sánchez-García I. Green MR, et al. Nat Commun. 2014 Jun 2;5:3904. doi: 10.1038/ncomms4904. Nat Commun. 2014. PMID: 24887457 Free PMC article.
Homeobox NKX2-3 promotes marginal-zone lymphomagenesis by activating B-cell receptor signalling and shaping lymphocyte dynamics.
Robles EF, Mena-Varas M, Barrio L, Merino-Cortes SV, Balogh P, Du MQ, Akasaka T, Parker A, Roa S, Panizo C, Martin-Guerrero I, Siebert R, Segura V, Agirre X, Macri-Pellizeri L, Aldaz B, Vilas-Zornoza A, Zhang S, Moody S, Calasanz MJ, Tousseyn T, Broccardo C, Brousset P, Campos-Sanchez E, Cobaleda C, Sanchez-Garcia I, Fernandez-Luna JL, Garcia-Muñoz R, Pena E, Bellosillo B, Salar A, Baptista MJ, Hernandez-Rivas JM, Gonzalez M, Terol MJ, Climent J, Ferrandez A, Sagaert X, Melnick AM, Prosper F, Oscier DG, Carrasco YR, Dyer MJ, Martinez-Climent JA. Robles EF, et al. Nat Commun. 2016 Jun 14;7:11889. doi: 10.1038/ncomms11889. Nat Commun. 2016. PMID: 27297662 Free PMC article.
ODZ1 allows glioblastoma to sustain invasiveness through a Myc-dependent transcriptional upregulation of RhoA.
Talamillo A, Grande L, Ruiz-Ontañon P, Velasquez C, Mollinedo P, Torices S, Sanchez-Gomez P, Aznar A, Esparis-Ogando A, Lopez-Lopez C, Lafita C, Berciano MT, Montero JA, Vazquez-Barquero A, Segura V, Villagra NT, Pandiella A, Lafarga M, Leon J, Martinez-Climent JA, Sanz-Moreno V, Fernandez-Luna JL. Talamillo A, et al. Oncogene. 2017 Mar 23;36(12):1733-1744. doi: 10.1038/onc.2016.341. Epub 2016 Sep 19. Oncogene. 2017. PMID: 27641332
114 results