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Page 1
Progesterone antagonist therapy in a Pelizaeus-Merzbacher mouse model.
Prukop T, Epplen DB, Nientiedt T, Wichert SP, Fledrich R, Stassart RM, Rossner MJ, Edgar JM, Werner HB, Nave KA, Sereda MW. Prukop T, et al. Am J Hum Genet. 2014 Apr 3;94(4):533-46. doi: 10.1016/j.ajhg.2014.03.001. Epub 2014 Mar 27. Am J Hum Genet. 2014. PMID: 24680886 Free PMC article.
Curcumin therapy in a Plp1 transgenic mouse model of Pelizaeus-Merzbacher disease.
Epplen DB, Prukop T, Nientiedt T, Albrecht P, Arlt FA, Stassart RM, Kassmann CM, Methner A, Nave KA, Werner HB, Sereda MW. Epplen DB, et al. Among authors: prukop t. Ann Clin Transl Neurol. 2015 Aug;2(8):787-96. doi: 10.1002/acn3.219. Epub 2015 Jun 24. Ann Clin Transl Neurol. 2015. PMID: 26339673 Free PMC article.
Targeting myelin lipid metabolism as a potential therapeutic strategy in a model of CMT1A neuropathy.
Fledrich R, Abdelaal T, Rasch L, Bansal V, Schütza V, Brügger B, Lüchtenborg C, Prukop T, Stenzel J, Rahman RU, Hermes D, Ewers D, Möbius W, Ruhwedel T, Katona I, Weis J, Klein D, Martini R, Brück W, Müller WC, Bonn S, Bechmann I, Nave KA, Stassart RM, Sereda MW. Fledrich R, et al. Among authors: prukop t. Nat Commun. 2018 Aug 2;9(1):3025. doi: 10.1038/s41467-018-05420-0. Nat Commun. 2018. PMID: 30072689 Free PMC article.
Synergistic PXT3003 therapy uncouples neuromuscular function from dysmyelination in male Charcot-Marie-Tooth disease type 1A (CMT1A) rats.
Prukop T, Wernick S, Boussicault L, Ewers D, Jäger K, Adam J, Winter L, Quintes S, Linhoff L, Barrantes-Freer A, Bartl M, Czesnik D, Zschüntzsch J, Schmidt J, Primas G, Laffaire J, Rinaudo P, Brureau A, Nabirotchkin S, Schwab MH, Nave KA, Hajj R, Cohen D, Sereda MW. Prukop T, et al. J Neurosci Res. 2020 Oct;98(10):1933-1952. doi: 10.1002/jnr.24679. Epub 2020 Jun 26. J Neurosci Res. 2020. PMID: 32588471
Biomarkers predict outcome in Charcot-Marie-Tooth disease 1A.
Fledrich R, Mannil M, Leha A, Ehbrecht C, Solari A, Pelayo-Negro AL, Berciano J, Schlotter-Weigel B, Schnizer TJ, Prukop T, Garcia-Angarita N, Czesnik D, Haberlová J, Mazanec R, Paulus W, Beissbarth T, Walter MC, Triaal C, Hogrel JY, Dubourg O, Schenone A, Baets J, De Jonghe P, Shy ME, Horvath R, Pareyson D, Seeman P, Young P, Sereda MW. Fledrich R, et al. Among authors: prukop t. J Neurol Neurosurg Psychiatry. 2017 Nov;88(11):941-952. doi: 10.1136/jnnp-2017-315721. Epub 2017 Aug 31. J Neurol Neurosurg Psychiatry. 2017. PMID: 28860329 Free PMC article.
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