Morley TJ - Search Results

1

In vivo evaluation of 18F-MNI698: an 18F-labeled radiotracer for imaging of serotonin 4 receptors in brain.

Tavares AA, Caillé F, Barret O, Papin C, Lee H, Morley TJ, Fowles K, Holden D, Seibyl JP, Alagille D, Tamagnan GD. Tavares AA, et al. Among authors: morley tj. J Nucl Med. 2014 May;55(5):858-64. doi: 10.2967/jnumed.113.132712. Epub 2014 Mar 31. J Nucl Med. 2014. PMID: 24686782 Free article.

2

Adenosine 2A receptor occupancy by tozadenant and preladenant in rhesus monkeys.

Barret O, Hannestad J, Alagille D, Vala C, Tavares A, Papin C, Morley T, Fowles K, Lee H, Seibyl J, Tytgat D, Laruelle M, Tamagnan G. Barret O, et al. J Nucl Med. 2014 Oct;55(10):1712-8. doi: 10.2967/jnumed.114.142067. Epub 2014 Jul 31. J Nucl Med. 2014. PMID: 25082853 Free article.

3

Kinetic Modeling of the Tau PET Tracer ¹⁸F-AV-1451 in Human Healthy Volunteers and Alzheimer Disease Subjects.

Barret O, Alagille D, Sanabria S, Comley RA, Weimer RM, Borroni E, Mintun M, Seneca N, Papin C, Morley T, Marek K, Seibyl JP, Tamagnan GD, Jennings D. Barret O, et al. J Nucl Med. 2017 Jul;58(7):1124-1131. doi: 10.2967/jnumed.116.182881. Epub 2016 Dec 1. J Nucl Med. 2017. PMID: 27908967 Free article. Clinical Trial.

4

Dopamine D₁ Receptor Agonist PET Tracer Development: Assessment in Nonhuman Primates.

Barret O, Zhang L, Alagille D, Constantinescu CC, Sandiego C, Papin C, Sullivan JM, Morley T, Carroll VM, Seibyl J, Chen J, Lee C, Villalobos A, Gray D, McCarthy TJ, Tamagnan G. Barret O, et al. Among authors: morley t. J Nucl Med. 2021 Sep 1;62(9):1307-1313. doi: 10.2967/jnumed.120.256008. Epub 2021 Feb 12. J Nucl Med. 2021. PMID: 33579806 Free PMC article.

5

Preclinical characterization of [¹⁸F]T-008, a novel PET imaging radioligand for cholesterol 24-hydroxylase.

Koike T, Constantinescu CC, Ikeda S, Nishi T, Sunahara E, Miyamoto M, Cole P, Barret O, Alagille D, Papin C, Morley T, Fowles K, Seibyl J, Tamagnan G, Kuroita T. Koike T, et al. Eur J Nucl Med Mol Imaging. 2022 Mar;49(4):1148-1156. doi: 10.1007/s00259-021-05565-z. Epub 2021 Oct 15. Eur J Nucl Med Mol Imaging. 2022. PMID: 34651220 Free PMC article.

6

Synthesis and biological evaluation of positron emission tomography radiotracers targeting serotonin 4 receptors in brain: [18F]MNI-698 and [18F]MNI-699.

Caillé F, Morley TJ, Tavares AA, Papin C, Twardy NM, Alagille D, Lee HS, Baldwin RM, Seibyl JP, Barret O, Tamagnan GD. Caillé F, et al. Among authors: morley tj. Bioorg Med Chem Lett. 2013 Dec 1;23(23):6243-7. doi: 10.1016/j.bmcl.2013.09.097. Epub 2013 Oct 9. Bioorg Med Chem Lett. 2013. PMID: 24157369

7

Whole-body biodistribution and dosimetry estimates of a novel radiotracer for imaging of serotonin 4 receptors in brain: [¹⁸F]MNI-698.

Tavares AA, Caillé F, Barret O, Papin C, Lee H, Morley TJ, Fowles K, Holden D, Seibyl JP, Alagille D, Tamagnan GD. Tavares AA, et al. Among authors: morley tj. Nucl Med Biol. 2014 May-Jun;41(5):432-9. doi: 10.1016/j.nucmedbio.2014.02.005. Epub 2014 Feb 28. Nucl Med Biol. 2014. PMID: 24674817

8

Identification and in vivo evaluation of a fluorine-18 rolipram analogue, [(18) F]MNI-617, as a radioligand for PDE4 imaging in mammalian brain.

Thomae D, Morley TJ, Lee HS, Barret O, Constantinescu C, Papin C, Baldwin RM, Tamagnan GD, Alagille D. Thomae D, et al. Among authors: morley tj. J Labelled Comp Radiopharm. 2016 May 15;59(5):205-13. doi: 10.1002/jlcr.3389. Epub 2016 Mar 22. J Labelled Comp Radiopharm. 2016. PMID: 27006107

9

Synthesis and in vivo Evaluation of Fluorine-18 and Iodine-123 Pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidine Derivatives as PET and SPECT Radiotracers for Mapping A2A Receptors.

Vala C, Morley TJ, Zhang X, Papin C, Tavares AA, Lee HS, Constantinescu C, Barret O, Carroll VM, Baldwin RM, Tamagnan GD, Alagille D. Vala C, et al. Among authors: morley tj. ChemMedChem. 2016 Sep 6;11(17):1936-43. doi: 10.1002/cmdc.201600219. Epub 2016 Jul 13. ChemMedChem. 2016. PMID: 27407017

10

The phosphodiesterase 10 positron emission tomography tracer, [18F]MNI-659, as a novel biomarker for early Huntington disease.

Russell DS, Barret O, Jennings DL, Friedman JH, Tamagnan GD, Thomae D, Alagille D, Morley TJ, Papin C, Papapetropoulos S, Waterhouse RN, Seibyl JP, Marek KL. Russell DS, et al. Among authors: morley tj. JAMA Neurol. 2014 Dec;71(12):1520-8. doi: 10.1001/jamaneurol.2014.1954. JAMA Neurol. 2014. PMID: 25322077

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