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Lack of type XV collagen causes a skeletal myopathy and cardiovascular defects in mice.
Eklund L, Piuhola J, Komulainen J, Sormunen R, Ongvarrasopone C, Fássler R, Muona A, Ilves M, Ruskoaho H, Takala TE, Pihlajaniemi T. Eklund L, et al. Among authors: piuhola j. Proc Natl Acad Sci U S A. 2001 Jan 30;98(3):1194-9. doi: 10.1073/pnas.98.3.1194. Epub 2001 Jan 23. Proc Natl Acad Sci U S A. 2001. PMID: 11158616 Free PMC article.
Collagen XV is necessary for modeling of the extracellular matrix and its deficiency predisposes to cardiomyopathy.
Rasi K, Piuhola J, Czabanka M, Sormunen R, Ilves M, Leskinen H, Rysä J, Kerkelä R, Janmey P, Heljasvaara R, Peuhkurinen K, Vuolteenaho O, Ruskoaho H, Vajkoczy P, Pihlajaniemi T, Eklund L. Rasi K, et al. Among authors: piuhola j. Circ Res. 2010 Nov 12;107(10):1241-52. doi: 10.1161/CIRCRESAHA.110.222133. Epub 2010 Sep 16. Circ Res. 2010. PMID: 20847313
37 results