Hasuoka A - Search Results

1

Molecular modeling, design, synthesis, and biological activity of 1H-pyrrolo[2,3-c]pyridine-7-amine derivatives as potassium-competitive acid blockers.

Arikawa Y, Hasuoka A, Hirase K, Inatomi N, Sato F, Hori Y, Takagi T, Tarui N, Kawamoto M, Kajino M. Arikawa Y, et al. Among authors: hasuoka a. Chem Pharm Bull (Tokyo). 2014;62(4):336-42. doi: 10.1248/cpb.c13-00878. Chem Pharm Bull (Tokyo). 2014. PMID: 24695343 Free article.

2

High-throughput screening of potassium-competitive acid blockers.

Kondo M, Kawamoto M, Hasuoka A, Kajino M, Inatomi N, Tarui N. Kondo M, et al. Among authors: hasuoka a. J Biomol Screen. 2012 Feb;17(2):177-82. doi: 10.1177/1087057111421004. Epub 2011 Sep 22. J Biomol Screen. 2012. PMID: 21940711

3

Discovery of a novel pyrrole derivative 1-[5-(2-fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl]-N-methylmethanamine fumarate (TAK-438) as a potassium-competitive acid blocker (P-CAB).

Arikawa Y, Nishida H, Kurasawa O, Hasuoka A, Hirase K, Inatomi N, Hori Y, Matsukawa J, Imanishi A, Kondo M, Tarui N, Hamada T, Takagi T, Takeuchi T, Kajino M. Arikawa Y, et al. Among authors: hasuoka a. J Med Chem. 2012 May 10;55(9):4446-56. doi: 10.1021/jm300318t. Epub 2012 Apr 30. J Med Chem. 2012. PMID: 22512618

4

Discovery, synthesis, and biological evaluation of novel pyrrole derivatives as highly selective potassium-competitive acid blockers.

Nishida H, Hasuoka A, Arikawa Y, Kurasawa O, Hirase K, Inatomi N, Hori Y, Sato F, Tarui N, Imanishi A, Kondo M, Takagi T, Kajino M. Nishida H, et al. Among authors: hasuoka a. Bioorg Med Chem. 2012 Jun 15;20(12):3925-38. doi: 10.1016/j.bmc.2012.04.014. Epub 2012 Apr 14. Bioorg Med Chem. 2012. PMID: 22579619

5

Synthetic studies of five-membered heteroaromatic derivatives as potassium-competitive acid blockers (P-CABs).

Arikawa Y, Hasuoka A, Nishida H, Hirase K, Inatomi N, Takagi T, Tarui N, Kawamoto M, Imanishi A, Itoh F, Kajino M. Arikawa Y, et al. Among authors: hasuoka a. Bioorg Med Chem Lett. 2015;25(10):2037-40. doi: 10.1016/j.bmcl.2015.03.094. Epub 2015 Apr 6. Bioorg Med Chem Lett. 2015. PMID: 25891103

6

Synthesis and structure-activity relationships of TAN-1511 analogues as potent hematopoietic agents.

Itoh F, Nishikimi Y, Hasuoka A, Yoshioka Y, Yukishige K, Tanida S, Aono T. Itoh F, et al. Among authors: hasuoka a. Chem Pharm Bull (Tokyo). 1998 Feb;46(2):255-73. doi: 10.1248/cpb.46.255. Chem Pharm Bull (Tokyo). 1998. PMID: 9501461

7

Development of a stereoselective practical synthetic route to indolmycin, a candidate anti-H. pylori agent.

Hasuoka A, Nakayama Y, Adachi M, Kamiguchi H, Kamiyama K. Hasuoka A, et al. Chem Pharm Bull (Tokyo). 2001 Dec;49(12):1604-8. doi: 10.1248/cpb.49.1604. Chem Pharm Bull (Tokyo). 2001. PMID: 11767081 Free article.

8

Design, synthesis, and biological evaluation of 4-arylmethyl-1-phenylpyrazole and 4-aryloxy-1-phenylpyrazole derivatives as novel androgen receptor antagonists.

Yamamoto S, Tomita N, Suzuki Y, Suzaki T, Kaku T, Hara T, Yamaoka M, Kanzaki N, Hasuoka A, Baba A, Ito M. Yamamoto S, et al. Among authors: hasuoka a. Bioorg Med Chem. 2012 Apr 1;20(7):2338-52. doi: 10.1016/j.bmc.2012.02.005. Epub 2012 Feb 10. Bioorg Med Chem. 2012. PMID: 22391033

9

Design, synthesis, and biological evaluation of 3-aryl-3-hydroxy-1-phenylpyrrolidine derivatives as novel androgen receptor antagonists.

Yamamoto S, Kobayashi H, Kaku T, Aikawa K, Hara T, Yamaoka M, Kanzaki N, Hasuoka A, Baba A, Ito M. Yamamoto S, et al. Among authors: hasuoka a. Bioorg Med Chem. 2013 Jan 1;21(1):70-83. doi: 10.1016/j.bmc.2012.11.001. Epub 2012 Nov 12. Bioorg Med Chem. 2013. PMID: 23199477

10

Synthesis and anti-Helicobacter pylori activity of pyloricidin derivatives II. The combination of amino acid residues in the dipeptidic moiety and its effect on the anti-Helicobacter pylori activity.

Hasuoka A, Nishikimi Y, Nakayama Y, Kamiyama K, Nakao M, Miyagawa K, Nishimura O, Fujino M. Hasuoka A, et al. J Antibiot (Tokyo). 2002 May;55(5):499-507. doi: 10.7164/antibiotics.55.499. J Antibiot (Tokyo). 2002. PMID: 12139019 Free article.

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