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Chemo-enzymatic synthesis of silybin and 2,3-dehydrosilybin dimers.
Vavříková E, Vacek J, Valentová K, Marhol P, Ulrichová J, Kuzma M, Křen V. Vavříková E, et al. Among authors: marhol p. Molecules. 2014 Apr 2;19(4):4115-34. doi: 10.3390/molecules19044115. Molecules. 2014. PMID: 24699152 Free PMC article.
Synthesis and antiangiogenic activity of new silybin galloyl esters.
Gažák R, Valentová K, Fuksová K, Marhol P, Kuzma M, Medina MÁ, Oborná I, Ulrichová J, Křen V. Gažák R, et al. Among authors: marhol p. J Med Chem. 2011 Oct 27;54(20):7397-407. doi: 10.1021/jm201034h. Epub 2011 Oct 3. J Med Chem. 2011. PMID: 21928794
Antioxidant and antiviral activities of silybin fatty acid conjugates.
Gazák R, Purchartová K, Marhol P, Zivná L, Sedmera P, Valentová K, Kato N, Matsumura H, Kaihatsu K, Kren V. Gazák R, et al. Among authors: marhol p. Eur J Med Chem. 2010 Mar;45(3):1059-67. doi: 10.1016/j.ejmech.2009.11.056. Epub 2009 Dec 6. Eur J Med Chem. 2010. PMID: 20036447
Biotransformation of silybin and its congeners.
Křen V, Marhol P, Purchartová K, Gabrielová E, Modrianský M. Křen V, et al. Among authors: marhol p. Curr Drug Metab. 2013 Dec;14(10):1009-21. doi: 10.2174/1389200214666131118234507. Curr Drug Metab. 2013. PMID: 24261705 Review.
19 results