Yano T - Search Results

1

Characterization of the type 2 NADH:menaquinone oxidoreductases from Staphylococcus aureus and the bactericidal action of phenothiazines.

Schurig-Briccio LA, Yano T, Rubin H, Gennis RB. Schurig-Briccio LA, et al. Among authors: yano t. Biochim Biophys Acta. 2014 Jul;1837(7):954-63. doi: 10.1016/j.bbabio.2014.03.017. Epub 2014 Apr 5. Biochim Biophys Acta. 2014. PMID: 24709059 Free PMC article.

2

Steady-state kinetics and inhibitory action of antitubercular phenothiazines on mycobacterium tuberculosis type-II NADH-menaquinone oxidoreductase (NDH-2).

Yano T, Li LS, Weinstein E, Teh JS, Rubin H. Yano T, et al. J Biol Chem. 2006 Apr 28;281(17):11456-63. doi: 10.1074/jbc.M508844200. Epub 2006 Feb 9. J Biol Chem. 2006. PMID: 16469750 Free article.

3

Reduction of clofazimine by mycobacterial type 2 NADH:quinone oxidoreductase: a pathway for the generation of bactericidal levels of reactive oxygen species.

Yano T, Kassovska-Bratinova S, Teh JS, Winkler J, Sullivan K, Isaacs A, Schechter NM, Rubin H. Yano T, et al. J Biol Chem. 2011 Mar 25;286(12):10276-87. doi: 10.1074/jbc.M110.200501. Epub 2010 Dec 30. J Biol Chem. 2011. PMID: 21193400 Free PMC article.

4

Type II NADH: menaquinone oxidoreductase of Mycobacterium tuberculosis.

Teh JS, Yano T, Rubin H. Teh JS, et al. Among authors: yano t. Infect Disord Drug Targets. 2007 Jun;7(2):169-81. doi: 10.2174/187152607781001781. Infect Disord Drug Targets. 2007. PMID: 17970227 Review.

5

Mycobacterium tuberculosis type II NADH-menaquinone oxidoreductase catalyzes electron transfer through a two-site ping-pong mechanism and has two quinone-binding sites.

Yano T, Rahimian M, Aneja KK, Schechter NM, Rubin H, Scott CP. Yano T, et al. Biochemistry. 2014 Feb 25;53(7):1179-90. doi: 10.1021/bi4013897. Epub 2014 Feb 11. Biochemistry. 2014. PMID: 24447297 Free PMC article.

6

Small Molecules Targeting Mycobacterium tuberculosis Type II NADH Dehydrogenase Exhibit Antimycobacterial Activity.

Harbut MB, Yang B, Liu R, Yano T, Vilchèze C, Cheng B, Lockner J, Guo H, Yu C, Franzblau SG, Petrassi HM, Jacobs WR Jr, Rubin H, Chatterjee AK, Wang F. Harbut MB, et al. Among authors: yano t. Angew Chem Int Ed Engl. 2018 Mar 19;57(13):3478-3482. doi: 10.1002/anie.201800260. Epub 2018 Feb 22. Angew Chem Int Ed Engl. 2018. PMID: 29388301 Free PMC article.

7

Inhibitors of type II NADH:menaquinone oxidoreductase represent a class of antitubercular drugs.

Weinstein EA, Yano T, Li LS, Avarbock D, Avarbock A, Helm D, McColm AA, Duncan K, Lonsdale JT, Rubin H. Weinstein EA, et al. Among authors: yano t. Proc Natl Acad Sci U S A. 2005 Mar 22;102(12):4548-53. doi: 10.1073/pnas.0500469102. Epub 2005 Mar 14. Proc Natl Acad Sci U S A. 2005. PMID: 15767566 Free PMC article.

8

A high-throughput small-molecule screen to identify a novel chemical inhibitor of Clostridium difficile.

Katzianer DS, Yano T, Rubin H, Zhu J. Katzianer DS, et al. Among authors: yano t. Int J Antimicrob Agents. 2014 Jul;44(1):69-73. doi: 10.1016/j.ijantimicag.2014.03.007. Epub 2014 Apr 24. Int J Antimicrob Agents. 2014. PMID: 24837414 Free PMC article.

9

Acinetobacter baumannii OxPhos inhibitors as selective anti-infective agents.

Rubin H, Selwood T, Yano T, Weaver DG, Loughran HM, Costanzo MJ, Scott RW, Wrobel JE, Freeman KB, Reitz AB. Rubin H, et al. Among authors: yano t. Bioorg Med Chem Lett. 2015 Jan 15;25(2):378-83. doi: 10.1016/j.bmcl.2014.11.020. Epub 2014 Nov 22. Bioorg Med Chem Lett. 2015. PMID: 25496770

10

Identification of the residues involved in stabilization of the semiquinone radical in the high-affinity ubiquinone binding site in cytochrome bo(3) from Escherichia coli by site-directed mutagenesis and EPR spectroscopy.

Hellwig P, Yano T, Ohnishi T, Gennis RB. Hellwig P, et al. Among authors: yano t. Biochemistry. 2002 Aug 27;41(34):10675-9. doi: 10.1021/bi012146w. Biochemistry. 2002. PMID: 12186553

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