Richards A - Search Results

1

Characterization of a factor H mutation that perturbs the alternative pathway of complement in a family with membranoproliferative GN.

Wong EK, Anderson HE, Herbert AP, Challis RC, Brown P, Reis GS, Tellez JO, Strain L, Fluck N, Humphrey A, Macleod A, Richards A, Ahlert D, Santibanez-Koref M, Barlow PN, Marchbank KJ, Harris CL, Goodship TH, Kavanagh D. Wong EK, et al. Among authors: richards a. J Am Soc Nephrol. 2014 Nov;25(11):2425-33. doi: 10.1681/ASN.2013070732. Epub 2014 Apr 10. J Am Soc Nephrol. 2014. PMID: 24722444 Free PMC article.

2

Mutations in complement factor I predispose to development of atypical hemolytic uremic syndrome.

Kavanagh D, Kemp EJ, Mayland E, Winney RJ, Duffield JS, Warwick G, Richards A, Ward R, Goodship JA, Goodship TH. Kavanagh D, et al. Among authors: richards a. J Am Soc Nephrol. 2005 Jul;16(7):2150-5. doi: 10.1681/ASN.2005010103. Epub 2005 May 25. J Am Soc Nephrol. 2005. PMID: 15917334

3

Does complement factor B have a role in the pathogenesis of atypical HUS?

Kavanagh D, Kemp EJ, Richards A, Burgess RM, Mayland E, Goodship JA, Goodship TH. Kavanagh D, et al. Among authors: richards a. Mol Immunol. 2006 Mar;43(7):856-9. doi: 10.1016/j.molimm.2005.06.041. Epub 2005 Aug 2. Mol Immunol. 2006. PMID: 16061287

4

Atypical hemolytic uremic syndrome.

Kavanagh D, Goodship TH, Richards A. Kavanagh D, et al. Among authors: richards a. Semin Nephrol. 2013 Nov;33(6):508-30. doi: 10.1016/j.semnephrol.2013.08.003. Semin Nephrol. 2013. PMID: 24161037 Free PMC article. Review.

5

Complement Evasion Mediated by Enhancement of Captured Factor H: Implications for Protection of Self-Surfaces from Complement.

Herbert AP, Makou E, Chen ZA, Kerr H, Richards A, Rappsilber J, Barlow PN. Herbert AP, et al. Among authors: richards a. J Immunol. 2015 Nov 15;195(10):4986-98. doi: 10.4049/jimmunol.1501388. Epub 2015 Oct 12. J Immunol. 2015. PMID: 26459349 Free PMC article.

6

Disease-linked mutations in factor H reveal pivotal role of cofactor activity in self-surface-selective regulation of complement activation.

Kerr H, Wong E, Makou E, Yang Y, Marchbank K, Kavanagh D, Richards A, Herbert AP, Barlow PN. Kerr H, et al. Among authors: richards a. J Biol Chem. 2017 Aug 11;292(32):13345-13360. doi: 10.1074/jbc.M117.795088. Epub 2017 Jun 21. J Biol Chem. 2017. PMID: 28637873 Free PMC article.

7

Murine Factor H Co-Produced in Yeast With Protein Disulfide Isomerase Ameliorated C3 Dysregulation in Factor H-Deficient Mice.

Kerr H, Herbert AP, Makou E, Abramczyk D, Malik TH, Lomax-Browne H, Yang Y, Pappworth IY, Denton H, Richards A, Marchbank KJ, Pickering MC, Barlow PN. Kerr H, et al. Among authors: richards a. Front Immunol. 2021 May 12;12:681098. doi: 10.3389/fimmu.2021.681098. eCollection 2021. Front Immunol. 2021. PMID: 34054871 Free PMC article.

8

Impact of compound heterozygous complement factor H mutations on development of atypical hemolytic uremic syndrome-A pedigree revisited.

Johnson SA, Williams JM, Hakobyan S, Richards A, Perkins SJ, Marchbank KJ, Goodship TH, Morgan BP, Taylor CM, Savage CO. Johnson SA, et al. Among authors: richards a. Mol Immunol. 2010 Apr;47(7-8):1585-91. doi: 10.1016/j.molimm.2009.12.001. Epub 2010 Mar 20. Mol Immunol. 2010. PMID: 20304497

9

The genetics and pathogenesis of haemolytic uraemic syndrome and thrombotic thrombocytopenic purpura.

Richards A, Goodship JA, Goodship TH. Richards A, et al. Curr Opin Nephrol Hypertens. 2002 Jul;11(4):431-5. doi: 10.1097/00041552-200207000-00010. Curr Opin Nephrol Hypertens. 2002. PMID: 12105394 Review.

10

Mutations in CD46, a complement regulatory protein, predispose to atypical HUS.

Goodship TH, Liszewski MK, Kemp EJ, Richards A, Atkinson JP. Goodship TH, et al. Among authors: richards a. Trends Mol Med. 2004 May;10(5):226-31. doi: 10.1016/j.molmed.2004.03.006. Trends Mol Med. 2004. PMID: 15121049 Review.

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