Bussiere JL - Search Results

1

Infant cynomolgus monkeys exposed to denosumab in utero exhibit an osteoclast-poor osteopetrotic-like skeletal phenotype at birth and in the early postnatal period.

Boyce RW, Varela A, Chouinard L, Bussiere JL, Chellman GJ, Ominsky MS, Pyrah IT. Boyce RW, et al. Among authors: bussiere jl. Bone. 2014 Jul;64:314-25. doi: 10.1016/j.bone.2014.04.002. Epub 2014 Apr 13. Bone. 2014. PMID: 24727159

2

Reproductive toxicity of denosumab in cynomolgus monkeys.

Bussiere JL, Pyrah I, Boyce R, Branstetter D, Loomis M, Andrews-Cleavenger D, Farman C, Elliott G, Chellman G. Bussiere JL, et al. Reprod Toxicol. 2013 Dec;42:27-40. doi: 10.1016/j.reprotox.2013.07.018. Epub 2013 Jul 22. Reprod Toxicol. 2013. PMID: 23886817

3

Placental transfer of a fully human IgG2 monoclonal antibody in the cynomolgus monkey, rat, and rabbit: a comparative assessment from during organogenesis to late gestation.

Moffat GJ, Retter MW, Kwon G, Loomis M, Hock MB, Hall C, Bussiere J, Lewis EM, Chellman GJ. Moffat GJ, et al. Birth Defects Res B Dev Reprod Toxicol. 2014 Apr;101(2):178-88. doi: 10.1002/bdrb.21105. Birth Defects Res B Dev Reprod Toxicol. 2014. PMID: 24753333

4

Developmental and reproductive toxicology studies in nonhuman primates.

Chellman GJ, Bussiere JL, Makori N, Martin PL, Ooshima Y, Weinbauer GF. Chellman GJ, et al. Among authors: bussiere jl. Birth Defects Res B Dev Reprod Toxicol. 2009 Dec;86(6):446-62. doi: 10.1002/bdrb.20216. Birth Defects Res B Dev Reprod Toxicol. 2009. PMID: 20025046 Review.

5

Nonclinical safety evaluation of erenumab, a CGRP receptor inhibitor for the prevention of migraine.

Bussiere JL, Davies R, Dean C, Xu C, Kim KH, Vargas HM, Chellman GJ, Balasubramanian G, Rubio-Beltran E, MaassenVanDenBrink A, Monticello TM. Bussiere JL, et al. Regul Toxicol Pharmacol. 2019 Aug;106:224-238. doi: 10.1016/j.yrtph.2019.05.013. Epub 2019 May 11. Regul Toxicol Pharmacol. 2019. PMID: 31085251 Free article. Review.

6

Assessment of menstrual cycle length in cynomolgus monkeys as a female fertility endpoint of a biopharmaceutical in a 6 month toxicity study.

Bussiere JL, Moffat G, Zhou L, Tarlo KS. Bussiere JL, et al. Regul Toxicol Pharmacol. 2013 Aug;66(3):269-78. doi: 10.1016/j.yrtph.2013.05.002. Epub 2013 May 13. Regul Toxicol Pharmacol. 2013. PMID: 23680404

7

Biological Characterization of a Stable Effector Functionless (SEFL) Monoclonal Antibody Scaffold in Vitro.

Liu L, Jacobsen FW, Everds N, Zhuang Y, Yu YB, Li N, Clark D, Nguyen MP, Fort M, Narayanan P, Kim K, Stevenson R, Narhi L, Gunasekaran K, Bussiere JL. Liu L, et al. Among authors: bussiere jl. J Biol Chem. 2017 Feb 3;292(5):1876-1883. doi: 10.1074/jbc.M116.748707. Epub 2016 Dec 19. J Biol Chem. 2017. PMID: 27994063 Free PMC article.

8

An open-label study in healthy men to evaluate the risk of seminal fluid transmission of denosumab to pregnant partners.

Sohn W, Lee E, Kankam MK, Egbuna O, Moffat G, Bussiere J, Padhi D, Ng E, Kumar S, Slatter JG. Sohn W, et al. Br J Clin Pharmacol. 2016 Feb;81(2):362-9. doi: 10.1111/bcp.12798. Epub 2015 Dec 5. Br J Clin Pharmacol. 2016. PMID: 26447647 Free PMC article. Clinical Trial.

9

A comparison of effects on reproduction and neonatal development in cynomolgus monkeys given human soluble IL-4R and mice given murine soluble IL-4R.

Carlock LL, Cowan LA, Oneda S, Hoberman A, Wang DD, Hanna R, Bussiere JL. Carlock LL, et al. Among authors: bussiere jl. Regul Toxicol Pharmacol. 2009 Apr;53(3):226-34. doi: 10.1016/j.yrtph.2009.02.001. Epub 2009 Feb 13. Regul Toxicol Pharmacol. 2009. PMID: 19217923

10

Phosphatidylinositol 3-Kinase δ Inhibitor-Induced Immunomodulation and Secondary Opportunistic Infection in the Cynomolgus Monkey (Macaca fascicularis).

Werner JA, Ishida K, Wisler J, Karbowski C, Kalanzi J, Bussiere J, Monticello TM. Werner JA, et al. Toxicol Pathol. 2020 Dec;48(8):949-964. doi: 10.1177/0192623320966238. Epub 2020 Nov 28. Toxicol Pathol. 2020. PMID: 33252030

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