Chellman GJ - Search Results

1

Infant cynomolgus monkeys exposed to denosumab in utero exhibit an osteoclast-poor osteopetrotic-like skeletal phenotype at birth and in the early postnatal period.

Boyce RW, Varela A, Chouinard L, Bussiere JL, Chellman GJ, Ominsky MS, Pyrah IT. Boyce RW, et al. Among authors: chellman gj. Bone. 2014 Jul;64:314-25. doi: 10.1016/j.bone.2014.04.002. Epub 2014 Apr 13. Bone. 2014. PMID: 24727159

2

Reproductive toxicity of denosumab in cynomolgus monkeys.

Bussiere JL, Pyrah I, Boyce R, Branstetter D, Loomis M, Andrews-Cleavenger D, Farman C, Elliott G, Chellman G. Bussiere JL, et al. Reprod Toxicol. 2013 Dec;42:27-40. doi: 10.1016/j.reprotox.2013.07.018. Epub 2013 Jul 22. Reprod Toxicol. 2013. PMID: 23886817

3

Investigation of maternal and fetal exposure to an IgG2 monoclonal antibody following biweekly intravaginal administration to cynomolgus monkeys throughout pregnancy.

Moffat GJ, Davies R, Kwon G, Retter MW, Chellman GJ, Kanapuram S, Moore M, Loomis M, Wang W, Pyrah IT. Moffat GJ, et al. Among authors: chellman gj. Reprod Toxicol. 2014 Sep;48:132-7. doi: 10.1016/j.reprotox.2014.05.003. Epub 2014 May 22. Reprod Toxicol. 2014. PMID: 24859271

4

Developmental and reproductive toxicology studies in nonhuman primates.

Chellman GJ, Bussiere JL, Makori N, Martin PL, Ooshima Y, Weinbauer GF. Chellman GJ, et al. Birth Defects Res B Dev Reprod Toxicol. 2009 Dec;86(6):446-62. doi: 10.1002/bdrb.20216. Birth Defects Res B Dev Reprod Toxicol. 2009. PMID: 20025046 Review.

5

Nonclinical safety evaluation of erenumab, a CGRP receptor inhibitor for the prevention of migraine.

Bussiere JL, Davies R, Dean C, Xu C, Kim KH, Vargas HM, Chellman GJ, Balasubramanian G, Rubio-Beltran E, MaassenVanDenBrink A, Monticello TM. Bussiere JL, et al. Among authors: chellman gj. Regul Toxicol Pharmacol. 2019 Aug;106:224-238. doi: 10.1016/j.yrtph.2019.05.013. Epub 2019 May 11. Regul Toxicol Pharmacol. 2019. PMID: 31085251 Free article. Review.

6

Placental transfer of a fully human IgG2 monoclonal antibody in the cynomolgus monkey, rat, and rabbit: a comparative assessment from during organogenesis to late gestation.

Moffat GJ, Retter MW, Kwon G, Loomis M, Hock MB, Hall C, Bussiere J, Lewis EM, Chellman GJ. Moffat GJ, et al. Among authors: chellman gj. Birth Defects Res B Dev Reprod Toxicol. 2014 Apr;101(2):178-88. doi: 10.1002/bdrb.21105. Birth Defects Res B Dev Reprod Toxicol. 2014. PMID: 24753333

7

Assessment of ixekizumab, an interleukin-17A monoclonal antibody, for potential effects on reproduction and development, including immune system function, in cynomolgus monkeys.

Clarke DO, Hilbish KG, Waters DG, Newcomb DL, Chellman GJ. Clarke DO, et al. Among authors: chellman gj. Reprod Toxicol. 2015 Dec;58:160-73. doi: 10.1016/j.reprotox.2015.10.008. Epub 2015 Oct 19. Reprod Toxicol. 2015. PMID: 26482726

8

Developmental and peri-postnatal study in cynomolgus monkeys with belimumab, a monoclonal antibody directed against B-lymphocyte stimulator.

Auyeung-Kim DJ, Devalaraja MN, Migone TS, Cai W, Chellman GJ. Auyeung-Kim DJ, et al. Among authors: chellman gj. Reprod Toxicol. 2009 Dec;28(4):443-55. doi: 10.1016/j.reprotox.2009.07.002. Epub 2009 Jul 23. Reprod Toxicol. 2009. PMID: 19631735

9

An Enhanced Pre- and Postnatal Development Study in Cynomolgus Monkeys with Tabalumab: A Human IgG4 Monoclonal Antibody.

Breslin WJ, Hilbish KG, Martin JA, Halstead CA, Newcomb DL, Chellman GJ. Breslin WJ, et al. Among authors: chellman gj. Birth Defects Res B Dev Reprod Toxicol. 2015 Jun;104(3):100-16. doi: 10.1002/bdrb.21146. Epub 2015 Jul 20. Birth Defects Res B Dev Reprod Toxicol. 2015. PMID: 26195230

10

Evaluation of early fetal exposure to vaginally-administered metronidazole in pregnant cynomolgus monkeys.

Thompson KE, Newcomb DL, Moffat GJ, Zalikowski J, Chellman GJ, McNerney ME. Thompson KE, et al. Among authors: chellman gj. Reprod Toxicol. 2016 Jan;59:17-21. doi: 10.1016/j.reprotox.2015.10.013. Epub 2015 Oct 30. Reprod Toxicol. 2016. PMID: 26524246

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