Ominsky MS - Search Results

1

Infant cynomolgus monkeys exposed to denosumab in utero exhibit an osteoclast-poor osteopetrotic-like skeletal phenotype at birth and in the early postnatal period.

Boyce RW, Varela A, Chouinard L, Bussiere JL, Chellman GJ, Ominsky MS, Pyrah IT. Boyce RW, et al. Among authors: ominsky ms. Bone. 2014 Jul;64:314-25. doi: 10.1016/j.bone.2014.04.002. Epub 2014 Apr 13. Bone. 2014. PMID: 24727159

2

Effects of sclerostin antibodies in animal models of osteoporosis.

Ominsky MS, Boyce RW, Li X, Ke HZ. Ominsky MS, et al. Bone. 2017 Mar;96:63-75. doi: 10.1016/j.bone.2016.10.019. Epub 2016 Oct 24. Bone. 2017. PMID: 27789417 Review.

3

Decreased bone remodeling and porosity are associated with improved bone strength in ovariectomized cynomolgus monkeys treated with denosumab, a fully human RANKL antibody.

Kostenuik PJ, Smith SY, Jolette J, Schroeder J, Pyrah I, Ominsky MS. Kostenuik PJ, et al. Among authors: ominsky ms. Bone. 2011 Aug;49(2):151-61. doi: 10.1016/j.bone.2011.03.769. Epub 2011 Mar 30. Bone. 2011. PMID: 21457806

4

Denosumab, a fully human RANKL antibody, reduced bone turnover markers and increased trabecular and cortical bone mass, density, and strength in ovariectomized cynomolgus monkeys.

Ominsky MS, Stouch B, Schroeder J, Pyrah I, Stolina M, Smith SY, Kostenuik PJ. Ominsky MS, et al. Bone. 2011 Aug;49(2):162-73. doi: 10.1016/j.bone.2011.04.001. Epub 2011 Apr 9. Bone. 2011. PMID: 21497676

5

Sustained Modeling-Based Bone Formation During Adulthood in Cynomolgus Monkeys May Contribute to Continuous BMD Gains With Denosumab.

Ominsky MS, Libanati C, Niu QT, Boyce RW, Kostenuik PJ, Wagman RB, Baron R, Dempster DW. Ominsky MS, et al. J Bone Miner Res. 2015 Jul;30(7):1280-9. doi: 10.1002/jbmr.2480. J Bone Miner Res. 2015. PMID: 25684625 Free article.

6

Differential temporal effects of sclerostin antibody and parathyroid hormone on cancellous and cortical bone and quantitative differences in effects on the osteoblast lineage in young intact rats.

Ominsky MS, Brown DL, Van G, Cordover D, Pacheco E, Frazier E, Cherepow L, Higgins-Garn M, Aguirre JI, Wronski TJ, Stolina M, Zhou L, Pyrah I, Boyce RW. Ominsky MS, et al. Bone. 2015 Dec;81:380-391. doi: 10.1016/j.bone.2015.08.007. Epub 2015 Aug 8. Bone. 2015. PMID: 26261096 Free article.

7

Finite Element Analysis of Denosumab Treatment Effects on Vertebral Strength in Ovariectomized Cynomolgus Monkeys.

Lee DC, Varela A, Kostenuik PJ, Ominsky MS, Keaveny TM. Lee DC, et al. Among authors: ominsky ms. J Bone Miner Res. 2016 Aug;31(8):1586-95. doi: 10.1002/jbmr.2830. Epub 2016 Apr 25. J Bone Miner Res. 2016. PMID: 27149403 Free article.

8

Romosozumab Improves Bone Mass and Strength While Maintaining Bone Quality in Ovariectomized Cynomolgus Monkeys.

Ominsky MS, Boyd SK, Varela A, Jolette J, Felx M, Doyle N, Mellal N, Smith SY, Locher K, Buntich S, Pyrah I, Boyce RW. Ominsky MS, et al. J Bone Miner Res. 2017 Apr;32(4):788-801. doi: 10.1002/jbmr.3036. Epub 2016 Dec 13. J Bone Miner Res. 2017. PMID: 27865001 Free article.

9

Kinetic reconstruction reveals time-dependent effects of romosozumab on bone formation and osteoblast function in vertebral cancellous and cortical bone in cynomolgus monkeys.

Boyce RW, Niu QT, Ominsky MS. Boyce RW, et al. Among authors: ominsky ms. Bone. 2017 Aug;101:77-87. doi: 10.1016/j.bone.2017.04.005. Epub 2017 Apr 18. Bone. 2017. PMID: 28428078 Free article.

10

Abaloparatide, a novel osteoanabolic PTHrP analog, increases cortical and trabecular bone mass and architecture in orchiectomized rats by increasing bone formation without increasing bone resorption.

Chandler H, Lanske B, Varela A, Guillot M, Boyer M, Brown J, Pierce A, Ominsky M, Mitlak B, Baron R, Kostenuik P, Hattersley G. Chandler H, et al. Bone. 2019 Mar;120:148-155. doi: 10.1016/j.bone.2018.10.012. Epub 2018 Oct 19. Bone. 2019. PMID: 30343166

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