Purdy GE - Search Results

1

Crystal structure of the transcriptional regulator Rv0678 of Mycobacterium tuberculosis.

Radhakrishnan A, Kumar N, Wright CC, Chou TH, Tringides ML, Bolla JR, Lei HT, Rajashankar KR, Su CC, Purdy GE, Yu EW. Radhakrishnan A, et al. Among authors: purdy ge. J Biol Chem. 2014 Jun 6;289(23):16526-40. doi: 10.1074/jbc.M113.538959. Epub 2014 Apr 15. J Biol Chem. 2014. PMID: 24737322 Free PMC article.

2

MmpL11 protein transports mycolic acid-containing lipids to the mycobacterial cell wall and contributes to biofilm formation in Mycobacterium smegmatis.

Pacheco SA, Hsu FF, Powers KM, Purdy GE. Pacheco SA, et al. Among authors: purdy ge. J Biol Chem. 2013 Aug 16;288(33):24213-22. doi: 10.1074/jbc.M113.473371. Epub 2013 Jul 8. J Biol Chem. 2013. PMID: 23836904 Free PMC article.

3

Crystal structure of the transcriptional regulator Rv1219c of Mycobacterium tuberculosis.

Kumar N, Radhakrishnan A, Wright CC, Chou TH, Lei HT, Bolla JR, Tringides ML, Rajashankar KR, Su CC, Purdy GE, Yu EW. Kumar N, et al. Among authors: purdy ge. Protein Sci. 2014 Apr;23(4):423-32. doi: 10.1002/pro.2424. Epub 2014 Mar 10. Protein Sci. 2014. PMID: 24424575 Free PMC article.

4

Crystal structure of the Mycobacterium tuberculosis transcriptional regulator Rv0302.

Chou TH, Delmar JA, Wright CC, Kumar N, Radhakrishnan A, Doh JK, Licon MH, Bolla JR, Lei HT, Rajashankar KR, Su CC, Purdy GE, Yu EW. Chou TH, et al. Among authors: purdy ge. Protein Sci. 2015 Dec;24(12):1942-55. doi: 10.1002/pro.2802. Epub 2015 Sep 29. Protein Sci. 2015. PMID: 26362239 Free PMC article.

5

Structural Basis for the Regulation of the MmpL Transporters of Mycobacterium tuberculosis.

Delmar JA, Chou TH, Wright CC, Licon MH, Doh JK, Radhakrishnan A, Kumar N, Lei HT, Bolla JR, Rajashankar KR, Su CC, Purdy GE, Yu EW. Delmar JA, et al. Among authors: purdy ge. J Biol Chem. 2015 Nov 20;290(47):28559-28574. doi: 10.1074/jbc.M115.683797. Epub 2015 Sep 22. J Biol Chem. 2015. PMID: 26396194 Free PMC article.

6

The Mycobacterium tuberculosis MmpL11 Cell Wall Lipid Transporter Is Important for Biofilm Formation, Intracellular Growth, and Nonreplicating Persistence.

Wright CC, Hsu FF, Arnett E, Dunaj JL, Davidson PM, Pacheco SA, Harriff MJ, Lewinsohn DM, Schlesinger LS, Purdy GE. Wright CC, et al. Among authors: purdy ge. Infect Immun. 2017 Jul 19;85(8):e00131-17. doi: 10.1128/IAI.00131-17. Print 2017 Aug. Infect Immun. 2017. PMID: 28507063 Free PMC article.

7

MmpL3 is a lipid transporter that binds trehalose monomycolate and phosphatidylethanolamine.

Su CC, Klenotic PA, Bolla JR, Purdy GE, Robinson CV, Yu EW. Su CC, et al. Among authors: purdy ge. Proc Natl Acad Sci U S A. 2019 Jun 4;116(23):11241-11246. doi: 10.1073/pnas.1901346116. Epub 2019 May 21. Proc Natl Acad Sci U S A. 2019. PMID: 31113875 Free PMC article.

8

Structural and functional evidence that lipoprotein LpqN supports cell envelope biogenesis in Mycobacterium tuberculosis.

Melly GC, Stokas H, Dunaj JL, Hsu FF, Rajavel M, Su CC, Yu EW, Purdy GE. Melly GC, et al. Among authors: purdy ge. J Biol Chem. 2019 Oct 25;294(43):15711-15723. doi: 10.1074/jbc.RA119.008781. Epub 2019 Aug 30. J Biol Chem. 2019. PMID: 31471317 Free PMC article.

9

M. tuberculosis AlkX Encoded by rv3249c Regulates a Conserved Alkane Hydroxylase System That Is Important for Replication in Macrophages and Biofilm Formation.

Stokas H, Rhodes HL, Simmons MB, Zhang R, Wright CC, Purdy GE. Stokas H, et al. Among authors: purdy ge. Microbiol Spectr. 2022 Aug 31;10(4):e0196922. doi: 10.1128/spectrum.01969-22. Epub 2022 Aug 8. Microbiol Spectr. 2022. PMID: 35938806 Free PMC article.

10

Structures of the mycobacterial MmpL4 and MmpL5 transporters provide insights into their role in siderophore export and iron acquisition.

Maharjan R, Zhang Z, Klenotic PA, Gregor WD, Tringides ML, Cui M, Purdy GE, Yu EW. Maharjan R, et al. Among authors: purdy ge. PLoS Biol. 2024 Oct 18;22(10):e3002874. doi: 10.1371/journal.pbio.3002874. eCollection 2024 Oct. PLoS Biol. 2024. PMID: 39423221 Free PMC article.

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