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Nor-1, a novel incretin-responsive regulator of insulin genes and insulin secretion.
Ordelheide AM, Gerst F, Rothfuss O, Heni M, Haas C, Thielker I, Herzberg-Schäfer S, Böhm A, Machicao F, Ullrich S, Stefan N, Fritsche A, Häring HU, Staiger H. Ordelheide AM, et al. Among authors: ullrich s. Mol Metab. 2013 Jun 17;2(3):243-55. doi: 10.1016/j.molmet.2013.06.003. eCollection 2013. Mol Metab. 2013. PMID: 24044104 Free PMC article.
What role do fat cells play in pancreatic tissue?
Gerst F, Wagner R, Oquendo MB, Siegel-Axel D, Fritsche A, Heni M, Staiger H, Häring HU, Ullrich S. Gerst F, et al. Among authors: ullrich s. Mol Metab. 2019 Jul;25:1-10. doi: 10.1016/j.molmet.2019.05.001. Epub 2019 May 7. Mol Metab. 2019. PMID: 31113756 Free PMC article. Review.
Common polymorphisms within the NR4A3 locus, encoding the orphan nuclear receptor Nor-1, are associated with enhanced beta-cell function in non-diabetic subjects.
Weyrich P, Staiger H, Stancáková A, Schäfer SA, Kirchhoff K, Ullrich S, Ranta F, Gallwitz B, Stefan N, Machicao F, Kuusisto J, Laakso M, Fritsche A, Häring HU. Weyrich P, et al. Among authors: ullrich s. BMC Med Genet. 2009 Aug 14;10:77. doi: 10.1186/1471-2350-10-77. BMC Med Genet. 2009. PMID: 19682370 Free PMC article.
The impact of genetic variation in the G6PC2 gene on insulin secretion depends on glycemia.
Heni M, Ketterer C, Hart LM, Ranta F, van Haeften TW, Eekhoff EM, Dekker JM, Boomsma DI, Nijpels G, Kramer MH, Diamant M, Simonis-Bik AM, Heine RJ, de Geus EJ, Schäfer SA, Machicao F, Ullrich S, Thamer C, Stefan N, Staiger H, Häring HU, Fritsche A. Heni M, et al. Among authors: ullrich s. J Clin Endocrinol Metab. 2010 Dec;95(12):E479-84. doi: 10.1210/jc.2010-0860. Epub 2010 Sep 8. J Clin Endocrinol Metab. 2010. PMID: 20826583
Activation of extracellular signal-regulated protein kinases 1 and 2 (ERK1/2) by free fatty acid receptor 1 (FFAR1/GPR40) protects from palmitate-induced beta cell death, but plays no role in insulin secretion.
Panse M, Gerst F, Kaiser G, Teutsch CA, Dölker R, Wagner R, Häring HU, Ullrich S. Panse M, et al. Among authors: ullrich s. Cell Physiol Biochem. 2015;35(4):1537-45. doi: 10.1159/000373969. Epub 2015 Mar 12. Cell Physiol Biochem. 2015. PMID: 25792236 Free article.
Metabolic crosstalk between fatty pancreas and fatty liver: effects on local inflammation and insulin secretion.
Gerst F, Wagner R, Kaiser G, Panse M, Heni M, Machann J, Bongers MN, Sartorius T, Sipos B, Fend F, Thiel C, Nadalin S, Königsrainer A, Stefan N, Fritsche A, Häring HU, Ullrich S, Siegel-Axel D. Gerst F, et al. Among authors: ullrich s. Diabetologia. 2017 Nov;60(11):2240-2251. doi: 10.1007/s00125-017-4385-1. Epub 2017 Aug 8. Diabetologia. 2017. PMID: 28791439
Point mutation of Ffar1 abrogates fatty acid-dependent insulin secretion, but protects against HFD-induced glucose intolerance.
Sabrautzki S, Kaiser G, Przemeck GKH, Gerst F, Lorza-Gil E, Panse M, Sartorius T, Hoene M, Marschall S, Häring HU, Hrabě de Angelis M, Ullrich S. Sabrautzki S, et al. Among authors: ullrich s. Mol Metab. 2017 Oct;6(10):1304-1312. doi: 10.1016/j.molmet.2017.07.007. Epub 2017 Jul 18. Mol Metab. 2017. PMID: 29031729 Free PMC article.
649 results