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Myostatin is a key mediator between energy metabolism and endurance capacity of skeletal muscle.
Mouisel E, Relizani K, Mille-Hamard L, Denis R, Hourdé C, Agbulut O, Patel K, Arandel L, Morales-Gonzalez S, Vignaud A, Garcia L, Ferry A, Luquet S, Billat V, Ventura-Clapier R, Schuelke M, Amthor H. Mouisel E, et al. Among authors: amthor h. Am J Physiol Regul Integr Comp Physiol. 2014 Aug 15;307(4):R444-54. doi: 10.1152/ajpregu.00377.2013. Epub 2014 Jun 25. Am J Physiol Regul Integr Comp Physiol. 2014. PMID: 24965795 Free article.
Blockade of ActRIIB signaling triggers muscle fatigability and metabolic myopathy.
Relizani K, Mouisel E, Giannesini B, Hourdé C, Patel K, Morales Gonzalez S, Jülich K, Vignaud A, Piétri-Rouxel F, Fortin D, Garcia L, Blot S, Ritvos O, Bendahan D, Ferry A, Ventura-Clapier R, Schuelke M, Amthor H. Relizani K, et al. Among authors: amthor h. Mol Ther. 2014 Aug;22(8):1423-1433. doi: 10.1038/mt.2014.90. Epub 2014 May 27. Mol Ther. 2014. PMID: 24861054 Free PMC article.
BMP signaling controls muscle mass.
Sartori R, Schirwis E, Blaauw B, Bortolanza S, Zhao J, Enzo E, Stantzou A, Mouisel E, Toniolo L, Ferry A, Stricker S, Goldberg AL, Dupont S, Piccolo S, Amthor H, Sandri M. Sartori R, et al. Among authors: amthor h. Nat Genet. 2013 Nov;45(11):1309-18. doi: 10.1038/ng.2772. Epub 2013 Sep 29. Nat Genet. 2013. PMID: 24076600
BMP signaling regulates satellite cell-dependent postnatal muscle growth.
Stantzou A, Schirwis E, Swist S, Alonso-Martin S, Polydorou I, Zarrouki F, Mouisel E, Beley C, Julien A, Le Grand F, Garcia L, Colnot C, Birchmeier C, Braun T, Schuelke M, Relaix F, Amthor H. Stantzou A, et al. Among authors: amthor h. Development. 2017 Aug 1;144(15):2737-2747. doi: 10.1242/dev.144089. Epub 2017 Jul 10. Development. 2017. PMID: 28694257 Free PMC article.
Muscle hypertrophy driven by myostatin blockade does not require stem/precursor-cell activity.
Amthor H, Otto A, Vulin A, Rochat A, Dumonceaux J, Garcia L, Mouisel E, Hourdé C, Macharia R, Friedrichs M, Relaix F, Zammit PS, Matsakas A, Patel K, Partridge T. Amthor H, et al. Proc Natl Acad Sci U S A. 2009 May 5;106(18):7479-84. doi: 10.1073/pnas.0811129106. Epub 2009 Apr 21. Proc Natl Acad Sci U S A. 2009. PMID: 19383783 Free PMC article.
64 results