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Hepatitis C virus core protein inhibits interferon production by a human plasmacytoid dendritic cell line and dysregulates interferon regulatory factor-7 and signal transducer and activator of transcription (STAT) 1 protein expression.
Stone AE, Mitchell A, Brownell J, Miklin DJ, Golden-Mason L, Polyak SJ, Gale MJ Jr, Rosen HR. Stone AE, et al. PLoS One. 2014 May 1;9(5):e95627. doi: 10.1371/journal.pone.0095627. eCollection 2014. PLoS One. 2014. PMID: 24788809 Free PMC article.
Hepatitis C virus infection induces autocrine interferon signaling by human liver endothelial cells and release of exosomes, which inhibits viral replication.
Giugliano S, Kriss M, Golden-Mason L, Dobrinskikh E, Stone AE, Soto-Gutierrez A, Mitchell A, Khetani SR, Yamane D, Stoddard M, Li H, Shaw GM, Edwards MG, Lemon SM, Gale M Jr, Shah VH, Rosen HR. Giugliano S, et al. Gastroenterology. 2015 Feb;148(2):392-402.e13. doi: 10.1053/j.gastro.2014.10.040. Epub 2014 Nov 4. Gastroenterology. 2015. PMID: 25447848 Free PMC article.
93 results