Guo RT - Search Results

1

Squalene synthase as a target for Chagas disease therapeutics.

Shang N, Li Q, Ko TP, Chan HC, Li J, Zheng Y, Huang CH, Ren F, Chen CC, Zhu Z, Galizzi M, Li ZH, Rodrigues-Poveda CA, Gonzalez-Pacanowska D, Veiga-Santos P, de Carvalho TM, de Souza W, Urbina JA, Wang AH, Docampo R, Li K, Liu YL, Oldfield E, Guo RT. Shang N, et al. Among authors: guo rt. PLoS Pathog. 2014 May 1;10(5):e1004114. doi: 10.1371/journal.ppat.1004114. eCollection 2014 May. PLoS Pathog. 2014. PMID: 24789335 Free PMC article.

2

Crystal structure of octaprenyl pyrophosphate synthase from hyperthermophilic Thermotoga maritima and mechanism of product chain length determination.

Guo RT, Kuo CJ, Chou CC, Ko TP, Shr HL, Liang PH, Wang AH. Guo RT, et al. J Biol Chem. 2004 Feb 6;279(6):4903-12. doi: 10.1074/jbc.M310161200. Epub 2003 Nov 15. J Biol Chem. 2004. PMID: 14617622 Free article.

3

Preliminary X-ray diffraction analysis of octaprenyl pyrophosphate synthase crystals from Thermotoga maritima and Escherichia coli.

Guo RT, Ko TP, Chou CC, Shr HL, Chu HM, Tsai YH, Liang PH, Wang AH. Guo RT, et al. Acta Crystallogr D Biol Crystallogr. 2003 Dec;59(Pt 12):2265-8. doi: 10.1107/s0907444903018985. Epub 2003 Nov 27. Acta Crystallogr D Biol Crystallogr. 2003. PMID: 14646090

4

A molecular ruler for chain elongation catalyzed by octaprenyl pyrophosphate synthase and its structure-based engineering to produce unprecedented long chain trans-prenyl products.

Guo RT, Kuo CJ, Ko TP, Chou CC, Liang PH, Wang AH. Guo RT, et al. Biochemistry. 2004 Jun 22;43(24):7678-86. doi: 10.1021/bi036336d. Biochemistry. 2004. PMID: 15196010

5

Structures of Selenomonas ruminantium phytase in complex with persulfated phytate: DSP phytase fold and mechanism for sequential substrate hydrolysis.

Chu HM, Guo RT, Lin TW, Chou CC, Shr HL, Lai HL, Tang TY, Cheng KJ, Selinger BL, Wang AH. Chu HM, et al. Among authors: guo rt. Structure. 2004 Nov;12(11):2015-24. doi: 10.1016/j.str.2004.08.010. Structure. 2004. PMID: 15530366 Free article.

6

Crystal structures of undecaprenyl pyrophosphate synthase in complex with magnesium, isopentenyl pyrophosphate, and farnesyl thiopyrophosphate: roles of the metal ion and conserved residues in catalysis.

Guo RT, Ko TP, Chen AP, Kuo CJ, Wang AH, Liang PH. Guo RT, et al. J Biol Chem. 2005 May 27;280(21):20762-74. doi: 10.1074/jbc.M502121200. Epub 2005 Mar 23. J Biol Chem. 2005. PMID: 15788389 Free article.

7

Homodimeric hexaprenyl pyrophosphate synthase from the thermoacidophilic crenarchaeon Sulfolobus solfataricus displays asymmetric subunit structures.

Sun HY, Ko TP, Kuo CJ, Guo RT, Chou CC, Liang PH, Wang AH. Sun HY, et al. Among authors: guo rt. J Bacteriol. 2005 Dec;187(23):8137-48. doi: 10.1128/JB.187.23.8137-8148.2005. J Bacteriol. 2005. PMID: 16291686 Free PMC article.

8

Crystal structure of type-III geranylgeranyl pyrophosphate synthase from Saccharomyces cerevisiae and the mechanism of product chain length determination.

Chang TH, Guo RT, Ko TP, Wang AH, Liang PH. Chang TH, et al. Among authors: guo rt. J Biol Chem. 2006 May 26;281(21):14991-5000. doi: 10.1074/jbc.M512886200. Epub 2006 Mar 22. J Biol Chem. 2006. PMID: 16554305 Free article.

9

Bisphosphonates target multiple sites in both cis- and trans-prenyltransferases.

Guo RT, Cao R, Liang PH, Ko TP, Chang TH, Hudock MP, Jeng WY, Chen CK, Zhang Y, Song Y, Kuo CJ, Yin F, Oldfield E, Wang AH. Guo RT, et al. Proc Natl Acad Sci U S A. 2007 Jun 12;104(24):10022-7. doi: 10.1073/pnas.0702254104. Epub 2007 May 29. Proc Natl Acad Sci U S A. 2007. PMID: 17535895 Free PMC article.

10

Crystal structure of IcaR, a repressor of the TetR family implicated in biofilm formation in Staphylococcus epidermidis.

Jeng WY, Ko TP, Liu CI, Guo RT, Liu CL, Shr HL, Wang AH. Jeng WY, et al. Among authors: guo rt. Nucleic Acids Res. 2008 Mar;36(5):1567-77. doi: 10.1093/nar/gkm1176. Epub 2008 Jan 21. Nucleic Acids Res. 2008. PMID: 18208836 Free PMC article.

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