Freeman J - Search Results

1

Pegylated interferons Lambda-1a and alfa-2a display different gene induction and cytokine and chemokine release profiles in whole blood, human hepatocytes and peripheral blood mononuclear cells.

Freeman J, Baglino S, Friborg J, Kraft Z, Gray T, Hill M, McPhee F, Hillson J, Lopez-Talavera JC, Wind-Rotolo M. Freeman J, et al. J Viral Hepat. 2014 Jun;21(6):e1-9. doi: 10.1111/jvh.12243. J Viral Hepat. 2014. PMID: 24827902 Clinical Trial.

2

Derivation of Phase 3 dosing for peginterferon lambda-1a in chronic hepatitis C, Part 2: Exposure-response analyses for efficacy and safety variables.

Hruska M, Wang X, Chan P, Ahmad A, Freeman J, Horga MA, Hillson J, Kansra V, Lopez-Talavera JC. Hruska M, et al. Among authors: freeman j. J Clin Pharmacol. 2015 Jan;55(1):73-80. doi: 10.1002/jcph.361. Epub 2014 Jul 24. J Clin Pharmacol. 2015. PMID: 25042797 Clinical Trial.

3

Pharmacokinetics and pharmacodynamics of pegylated interferon lambda-1 in cynomolgus monkeys.

Byrnes-Blake KA, Pederson S, Klucher KM, Anderson-Haley M, Miller DM, Lopez-Talavera JC, Freeman JA. Byrnes-Blake KA, et al. J Interferon Cytokine Res. 2012 May;32(5):198-206. doi: 10.1089/jir.2011.0075. Epub 2012 Jan 26. J Interferon Cytokine Res. 2012. PMID: 22280056

4

Derivation of Phase 3 dosing for peginterferon lambda-1a in chronic hepatitis C, Part 1: Modeling optimal treatment duration and sustained virologic response rates.

Wang X, Hruska M, Chan P, Ahmad A, Freeman J, Horga MA, Hillson J, Kansra V, Lopez-Talavera JC. Wang X, et al. Among authors: freeman j. J Clin Pharmacol. 2015 Jan;55(1):63-72. doi: 10.1002/jcph.363. Epub 2014 Jul 24. J Clin Pharmacol. 2015. PMID: 25043197 Clinical Trial.

5

Peginterferon Lambda-1a, a New Therapeutic for Hepatitis C Infection, from Bench to Clinic.

Andersen H, Meyer J, Freeman J, Doyle SE, Klucher K, Miller DM, Hausman D, Hillson JL. Andersen H, et al. Among authors: freeman j. J Clin Transl Hepatol. 2013 Dec;1(2):116-24. doi: 10.14218/JCTH.2013.00014. Epub 2013 Dec 15. J Clin Transl Hepatol. 2013. PMID: 26357610 Free PMC article. Review.

6

Phase 1b study of pegylated interferon lambda 1 with or without ribavirin in patients with chronic genotype 1 hepatitis C virus infection.

Muir AJ, Shiffman ML, Zaman A, Yoffe B, de la Torre A, Flamm S, Gordon SC, Marotta P, Vierling JM, Lopez-Talavera JC, Byrnes-Blake K, Fontana D, Freeman J, Gray T, Hausman D, Hunder NN, Lawitz E. Muir AJ, et al. Among authors: freeman j. Hepatology. 2010 Sep;52(3):822-32. doi: 10.1002/hep.23743. Hepatology. 2010. PMID: 20564352 Clinical Trial.

7

Interferon lambda as a potential new therapeutic for hepatitis C.

Miller DM, Klucher KM, Freeman JA, Hausman DF, Fontana D, Williams DE. Miller DM, et al. Ann N Y Acad Sci. 2009 Dec;1182:80-7. doi: 10.1111/j.1749-6632.2009.05241.x. Ann N Y Acad Sci. 2009. PMID: 20074277

8

Interleukin (IL) 31 induces in cynomolgus monkeys a rapid and intense itch response that can be inhibited by an IL-31 neutralizing antibody.

Lewis KE, Holdren MS, Maurer MF, Underwood S, Meengs B, Julien SH, Byrnes-Blake KA, Freeman JA, Bukowski TR, Wolf AC, Hamacher NB, Rixon MW, Dillon SR. Lewis KE, et al. Among authors: freeman ja. J Eur Acad Dermatol Venereol. 2017 Jan;31(1):142-150. doi: 10.1111/jdv.13794. Epub 2016 Aug 8. J Eur Acad Dermatol Venereol. 2017. PMID: 27501029

9

Recombinant interleukin-21 plus sorafenib for metastatic renal cell carcinoma: a phase 1/2 study.

Bhatia S, Curti B, Ernstoff MS, Gordon M, Heath EI, Miller WH Jr, Puzanov I, Quinn DI, Flaig TW, VanVeldhuizen P, Byrnes-Blake K, Freeman JA, Bittner R, Hunder N, Souza S, Thompson JA. Bhatia S, et al. J Immunother Cancer. 2014 Jan 27;2:2. doi: 10.1186/2051-1426-2-2. eCollection 2014. J Immunother Cancer. 2014. PMID: 24829759 Free PMC article.

10

What Is in a Name? Depression and Anxiety Symptoms in Collegiate Athletes With and Without a History of Concussion.

Dunbar HS, Donahue CC, Vela L, Freeman J, Resch JE. Dunbar HS, et al. Among authors: freeman j. J Sport Rehabil. 2025 Jan 11:1-11. doi: 10.1123/jsr.2024-0107. Online ahead of print. J Sport Rehabil. 2025. PMID: 39798558

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